166984-63-0 Usage
General Description
1-(5-O-(DIMETHOXYTRITYL)-BETA-D-2-DEOXYRIBOFURANOSYL)-3-NITROPYRROLE is a chemical compound used in the synthesis of oligonucleotides, which are important for genetic and molecular biology research. It contains a nitropyrrole group, which can be used in the design of DNA interstrand cross-links as potential anticancer agents. The compound also contains a 2-deoxyribofuranosyl group, which is a key component of DNA and RNA, and is often used in the construction of modified nucleosides and oligonucleotide analogs for biological studies. The DIMETHOXYTRITYL group serves as a protecting group during the synthesis of oligonucleotides, and is removed at the end of the process to yield the final product. Overall, 1-(5-O-(DIMETHOXYTRITYL)-BETA-D-2-DEOXYRIBOFURANOSYL)-3-NITROPYRROLE plays a crucial role in the chemical synthesis of nucleic acids and in the development of potential therapeutic agents.
Check Digit Verification of cas no
The CAS Registry Mumber 166984-63-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,6,9,8 and 4 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 166984-63:
(8*1)+(7*6)+(6*6)+(5*9)+(4*8)+(3*4)+(2*6)+(1*3)=190
190 % 10 = 0
So 166984-63-0 is a valid CAS Registry Number.
166984-63-0Relevant articles and documents
Synthesis, structure, and deoxyribonucleic acid sequencing with a universal nucleoside: 1-(2′-deoxy-β-D-ribofuranosyl)-3-nitropyrrole
Bergstrom, Donald E.,Zhang, Peiming,Toma, Pascal H.,Andrews, Philip C.,Nichols, Ruthann
, p. 1201 - 1209 (2007/10/02)
A nucleoside analogue, 1-(2′-deoxy-β-D-ribofuranosyl)-3-nitropyrrole (4) was designed to function as a universal replacement for any of the natural nucleosides in DNA sequences. Compound 4 was synthesized by the reaction of 3-nitropyrrole with sodium hydr