1670-69-5

Basic information

• Product Name: 1-Methyladenine
• Synonyms: 1-METHYLADENINE;9H-Purine-9-ethanol;N1-Methyladenine
• CAS NO: 1670-69-5
• Molecular Formula: C6H7N5
• Molecular Weight: 149.15
• Mol File: 1670-69-5.mol
• Article Data: 0

Chemical Properties

• Melting Point: 96℃
• Appearance: /
• Density: 1.48
• Storage Temp.: -20°C Freezer, Under inert atmosphere
• Solubility: Aqueous Base (Slightly, Heated, Sonicated), Water (Slightly, Heated, Sonicated)
• CAS DataBase Reference: 1-Methyladenine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Methyladenine(1670-69-5)
• EPA Substance Registry System: 1-Methyladenine(1670-69-5)

Safety Data

• Hazardous Substances Data: 1670-69-5(Hazardous Substances Data)

Usage

Uses

1-Methyladenine is an alkylated version of Adenine. When inserted into DNA, it is cytotoxic and mutagenic. In starfish oocytes, it is a maturation-inducing hormone.

Related news

Contribution of de novo synthesis of Gαs-proteins to 1-Methyladenine (cas 1670-69-5) production in starfish ovarian follicle cells stimulated by relaxin-like gonad-stimulating substance09/29/2019

In starfish, the peptide hormone gonad-stimulating substance (GSS) secreted from nervous tissue stimulates oocyte maturation to induce 1-methyladenine (1-MeAde) production by ovarian follicle cells. The hormonal action of GSS on follicle cells involves its receptor, G-proteins and adenylyl cycla...detailed

1-Methyladenine (cas 1670-69-5) production from ATP by starfish ovarian follicle cells09/28/2019

1-Methyladenine (1-MeAde), the oocyte maturation-inducing substance in starfish, is produced by ovarian follicle cells upon stimulation with a gonad-stimulating substance (GSS) released from the radial nerves. We have shown previously that GSS causes a reduction in the intracellular levels of AT...detailed

Quantum chemical study of 1-Methyladenine (cas 1670-69-5) and its spectra in gas phase and in solvent. I.10/01/2019

It is shown using the PM3 method that 1-methyladenine possesses four low-lying tautomeric forms, three of which are of the imino type. One of the imino forms, Ia is predominant and not energetically equivalent to the other ones. The effect of protonation on the spectra of these forms has been st...detailed

Effect of 1-Methyladenine (cas 1670-69-5) on thermodynamic stabilities of double-helical DNA structures09/27/2019

1-Methyladenine (m1A) alters T·A Watson–Crick to T·m1A Hoogsteen base pair. Owing to its conversion to N6-methyladenine (m6A) at higher temperatures, thermodynamic studies of m1A-containing DNAs using conventional melting methods are subject to the influence of m6A species. In this study, we ...detailed

Effect of 1-Methyladenine (cas 1670-69-5) on double-helical DNA structures09/26/2019

Methylation at the N1 site of adenine leads to the formation of cytotoxic 1-methyladenine (m1A). Since the N1 site of adenine is involved in the hydrogen bonding of T·A and A·T Watson–Crick base pairs, it is expected that the pairing interactions will be disrupted upon 1-methylation. In this ...detailed