167014-59-7Relevant academic research and scientific papers
Use of phenylacetamides as plant protectives having herbicidal and fungicidal effect
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, (2008/06/13)
The resent invention relates to the use of phenylacetamides as crop protection agents, to novel crop protection compositions comprising, as active compounds, phenylacetamides, and to novel phenylacetamides. The present invention provides the use of phenylacetamides of the formula I as crop protection agents having herbicidal and/or fungicidal action, where the radicals have the following meanings: A is an unsubstituted or substituted aryl radical; R1is an unsubstituted or substituted aryl radical; R2, R3are hydrogen, C1-C6-alkyl, C2-C6-alkenyl, C3-C7-cycloalkyl, C1-C6-alkylaryl, which may be unsubstituted or partially or fully halogenated or may carry one to three substituents selected from the group consisting of C1-C4-alkoxy, C1-C4-haloalkoxy, C1-C4-alkylthio, C3-C7-cycloalkyl, C5-C7-cycloalkenyl; R4is hydrogen or C1-C6-alkyl; R5is hydroxyl, C1-C4-alkoxy, aryl-C1-C4-alkoxy, aryloxy, and their agriculturally useful salts.
Heterocyclic-substituted alkylamide acat inhibitors
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Example 137, (2010/11/29)
Pharmaceutically useful compounds having ACAT inhibitory activity of the formula wherein n is 0, 1, or 2, for X other than tetrazole and n = 2 then R2 = R3 = H; R1 is phenyl, substituted phenyl, naphthyl, substituted naphthyl, a heteroaromatic group or a hydrocarbon group having from one to 18 carbon atoms; R2 and R3 are hydrogen, halo, hydroxy, alkyl, alkenyl, cycloalkyl, phenyl, substituted phenyl, a heteroaryl, or form a spiroalkyl group; x is a 5-membered heteromonocyclic group containing at least one to four heteroatoms selected from the group consisting of isothiazole, oxazole, thiazole, imidazole, furan, thiophene, pyrrole, tetrazole, 1,2,3-triazole, 1,2,4-oxadiazole, 1,3,4-oxadiazole, 1,3,4-thiadiazole, 1,2,4-triazole, and 1,2,4-oxadiazole said heteromonocyclic group being unsubstituted or substituted at any available position along the ring,
Heterocyclic amides: Inhibitors of acyl-CoA:cholesterol O-acyl transferase with hypocholesterolemic activity in several species and antiatherosclerotic activity in the rabbit
White, Andrew D.,Purchase II, Claude F.,Picard, Joseph A.,Anderson, Maureen K.,Mueller, Sandra Bak,Bocan, Thomas M. A.,Bousley, Richard F.,Hamelehle, Katherine L.,Krause, Brian R.,Lee, Peter,Stanfield, Richard L.,Reindel, James F.
, p. 3908 - 3919 (2007/10/03)
A series of heterocyclic amides were synthesized and evaluated as inhibitors of acyl-CoA: cholesterol O-acyltransferase (ACAT) in vitro and for cholesterol lowering in cholesterol-fed rats. Compounds were evaluated for cell-based macrophage ACAT inhibitio
