16705-20-7

Usage

General Description

2-(3-oxobutyl)-2,3-dihydrophthalazine-1,4-dione is a chemical compound with the molecular formula C11H12N2O4. It is a phthalazine derivative with a butyl group attached to the nitrogen atom. 2-(3-oxobutyl)-2,3-dihydrophthalazine-1,4-dione has potential pharmaceutical applications due to its structural resemblance to other biologically active compounds. It may exhibit various pharmacological properties, including antimicrobial, antifungal, and antioxidant activities. Further research is needed to explore its potential medical uses and evaluate its safety profile.

Upstream product

• 1445-69-8 2,3-dihydrophthalazine-1,4-dione 
• 78-94-4 methyl vinyl ketone 

Relevant academic research and scientific papers

2,3-dihydrophthalazine-1,4-diones

A compound having the structural formula STR1 wherein R1 is hydrogen, C1 -C6 alkyl, C2 -C6 carbalkoxyalkyl or phenyl substituted with C1 -C3 alkyl or halogen; R2 is hydrogen or C1 -C6 alkyl; and R3 and R4 are the same or different and are hydrogen, C1 -C3 alkyl, C1 -C3 alkoxy or halogen with the provisos that if R2, R3 and R4 are hydrogen, then R1 is not methyl, n-propyl or phenyl substituted with methyl in the ortho or para position; if R1, R2 and R3 are hydrogen then R4 is not hydrogen, methyl or methoxy; and if R1 and R2 are both n-propyl or n-butyl then R3 and R4 are not both hydrogen. These compounds demonstrate utility as hypolipidemic agents. The present invention is also directed to a process for controlling hyperlipidemia in mammals comprising treating mammals with a hyperlipidemia controlling effective amount of a compound having the above-identified structural formula wherein R1 is hydrogen, C1 -C6 alkyl, C2 -C6 carboxyalkyl, C2 -C6 carbalkoxyalkyl, phenyl or phenyl substituted with C1 -C3 alkyl or halogen; R2 is hydrogen or C1 -C6 alkyl; and R3 and R4 are the same or different and are hydrogen, C1 -C3 alkyl, C1 -C3 alkoxy or halogen. Yet another aspect of the present invention is embodied in a pharmaceutical composition comprising a compound having the above structural formula wherein R1 is hydrogen, C1 -C6 alkyl, C2 -C6 carboxyalkyl, C2 -C6 carbalkoxyalkyl, phenyl or phenyl substituted with C1 -C3 alkyl or halogen; R2 is hydrogen or C1 -C6 alkyl; and R3 and R4 are the same or different and are hydrogen, C1 -C3 alkyl, C1 -C3 alkoxy or halogen and a pharmaceutically acceptable carrier therefor.