1671-20-1Relevant academic research and scientific papers
Design and synthesis of N-alkylated saccharins as selective α-1a adrenergic receptor antagonists
Nerenberg, Jennie B.,Erb, Jill M.,Thompson, Wayne J.,Lee, Hee-Yoon,Guare, James P.,Munson, Peter M.,Bergman, Jeffrey M.,Huff, Joel R.,Broten, Theodore P.,Chang, Raymond S. L.,Chen, Tsing B.,O'Malley, Stacey,Schorn, Terry W.,Scott, Ann L.
, p. 2467 - 2472 (1998)
Benign prostatic hyperplasia can be managed pharmacologically with α-1 adrenergic receptor antagonists. Agents that demonstrate selectivity for the α-la receptor subtype may offer advantages in clinical applications with respect to hypotensive side effect
