167107-72-4

Upstream product

• 100-52-7 benzaldehyde 
• 110824-26-5 tert-butyl(diphenyl)(2-propynyloxy)silane 
• 88159-06-2 tert-butyl(diphenyl)(2-propynyloxy)silane 

Downstream Products

• 90924-12-2 3-phenyl-5-hydroxymethylisoxazole 
• 521980-61-0 acetic acid 4-(tert-butyl-diphenyl-silanyloxy)-1-phenyl-but-2-enyl ester 
• 521980-60-9 acetic acid 4-(tert-butyl-dimethyl-silanyloxy)-1-phenyl-but-2-enyl ester 
• 521980-59-6 Acetic acid (E)-1-phenyl-4-trimethylsilanyloxy-but-2-enyl ester 
• 947692-03-7 (E)-4-(tert-butyldimethylsilyloxy)-1-phenylbut-2-en-1-ol 
• 74141-11-0 trans-1-Phenyl-2-buten-1,4-diol 
• 29021-82-7 1-phenylbut-2-yne-1,4-diol 

Relevant academic research and scientific papers

One-pot synthesis of 3,5-disubstituted isoxazoles from propargylic alcohols through propargylic N-hydroxylamines

An efficient approach has been described for the synthesis of 3,5-disubstituted isoxazoles from propargylic alcohols. The strategy involves a one-pot p-TSA-catalyzed N-propargylation of protected hydroxylamines followed by a TBAF-mediated detosylative 5-endo-dig cyclization. The method was successfully used for the synthesis of various 3,5-disubstituted isoxazoles.

Regiocontrol in Pd-catalyzed allylic substitution with P,N-ligand

A racemic ligand, (±)-N-[2-(diphenylphosphino)naphthyl]-2- (pyrrolidinylmethyl)piperidine, has been found to exhibit better regioselectivity than the racemic Pfaltz ligand, BINAP and dppp in the palladium-catalyzed regioselective allylic substitution with