167172-40-9

Upstream product

• 1609003-85-1 3-(4-bromophenyl)-5-methylbenzofuran-2(3H)-one 
• 106-44-5 p-cresol 
• 107456-33-7 4-methylphenyl 4-bromobenzoate 

Downstream Products

• 257953-47-2 (4-bromo-phenyl)-(2-methoxy-5-methyl-phenyl)-methanone 
• 1225592-38-0 [2-(4-bromobenzoyl)-4-methylphenoxy]acetonitrile 
• 1578261-66-1 ethyl (N'-{2-[2-(4-bromobenzoyl)-4-methylphenoxy]acetyl}hydrazinocarbonyl)acetate 
• 1578261-57-0 2-[2-(4-bromobenzoyl)-4-methylphenoxy]acetohydrazide 
• 146010-25-5 ethyl [2-(4-bromobenzoyl)-4-methylphenoxy]acetate 

Relevant academic research and scientific papers

Nickel-Catalyzed Decarbonyloxidation of 3-Aryl Benzofuran-2(3H)-ones to 2-Hydroxybenzophenones

We have developed a protocol to facilitate the nickel-catalyzed decarbonyloxidation of 3-aryl benzofuran-2(3H)-ones to 2-hydroxybenzophenones under mild conditions, which is an efficient approach for the decarbonyloxidation of lactones in organic synthesis. A diverse range of substrates can undergo C(O)-O/C(O)-C bond cleavage to generate the target products in good yields. These 2-hydroxybenzophenones can be converted into a variety of compounds via reactions such as esterification, cyclization, and reduction.