1609003-85-1Relevant academic research and scientific papers
Nickel-Catalyzed Decarbonyloxidation of 3-Aryl Benzofuran-2(3H)-ones to 2-Hydroxybenzophenones
Tong, Zhou,Tang, Zhi,Au, Chak-Tong,Qiu, Renhua
, p. 8533 - 8543 (2020/07/16)
We have developed a protocol to facilitate the nickel-catalyzed decarbonyloxidation of 3-aryl benzofuran-2(3H)-ones to 2-hydroxybenzophenones under mild conditions, which is an efficient approach for the decarbonyloxidation of lactones in organic synthesis. A diverse range of substrates can undergo C(O)-O/C(O)-C bond cleavage to generate the target products in good yields. These 2-hydroxybenzophenones can be converted into a variety of compounds via reactions such as esterification, cyclization, and reduction.
A benzofuran compound and its efficient catalytic synthesis method
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Paragraph 0057; 0058, (2019/04/04)
The invention discloses a to trifluoromethanesulfonic acid nickel as catalyst, in order to mandelic acid and phenol as raw materials, and efficient synthesis of the benzofuran compound of the method, this method has the advantages of low cost, high yield,
Recyclable nickel-catalyzed C-H/O-H dual functionalization of phenols with mandelic acids for the synthesis of 3-aryl benzofuran-2(3: H)-ones under solvent-free conditions
Tang, Zhi,Tong, Zhou,Xu, Zhihui,Au, Chak-Tong,Qiu, Renhua,Yin, Shuang-Feng
supporting information, p. 2015 - 2022 (2019/04/27)
Herein, we developed a protocol for the efficient synthesis of 3-aryl benzofuran-2(3H)-ones under solvent-free conditions from phenols and mandelic acids using Ni(OTf)2 as a catalyst. A diverse range of mandelic acids and phenols undergo C-H/O-
Highly site-selective direct C-H bond functionalization of phenols with α-aryl-α-diazoacetates and diazooxindoles via gold catalysis
Yu, Zhunzhun,Ma, Ben,Chen, Mingjin,Wu, Hai-Hong,Liu, Lu,Zhang, Junliang
, p. 6904 - 6907 (2014/06/09)
An unprecedented direct C-H bond functionalization of unprotected phenols with α-aryl α-diazoacetates and diazooxindoles was developed. A tris(2,4-di-tert-butylphenyl) phosphite derived gold complex promoted the highly chemoselective and site-selective C-H bond functionalization of phenols and N-acylanilines with gold-carbene generated from the decomposition of diazo compounds, furnishing the corresponding products in moderate to excellent yields at rt. The salient features of this reaction include readily available starting materials, unprecedented C-H functionalization rather than X-H insertion, good substrate scope, mild conditions, high efficiency, and ease in further transformation. To the best of our knowledge, this is the first example of C-H functionalization of unprotected phenols with diazo compounds.
