167226-20-2Relevant academic research and scientific papers
Organocatalytic 1,4-Addition Reaction of 2-Formyl(thio)esters to Vinylketones: An Efficient Access to Acyclic Chiral Building Blocks with a Quaternary Carbon Stereocenter
Tatsumi, Toshifumi,Misaki, Tomonori,Sugimura, Takashi
supporting information, p. 18971 - 18974 (2016/01/26)
2-Formyl(thio)esters were utilized as pronucleophiles to obtain less-accessible acyclic chiral building blocks bearing versatile functional groups on a quaternary carbon atom for enantioselective 1,4-addition to vinylketones. To achieve high enantioselect
New class of amino-phosphinite chiral catalysts for the highly enantioselective addition of arylzinc reagents to aldehydes
Godoi, Marcelo,Alberto, Eduardo E.,Paix?o, Marcio W.,Soares, Liliana A.,Schneider, Paulo H.,Braga, Antonio L.
scheme or table, p. 1341 - 1345 (2010/04/02)
A new class of amino-phosphinite chiral ligands was prepared and applied in zinc-catalyzed addition of aryl boronic acids to aldehydes; the reaction furnished the diarylmethanols in excellent yields and with a high level of enantioselectivity (up to 93% ee).
Aziridin-2-yl methanols as organocatalysts in Diels-Alder reactions and Friedel-Crafts alkylations of N-methyl-pyrrole and N-methyl-indole
Bonini, Bianca F.,Capito, Elena,Comes-Franchini, Mauro,Fochi, Mariafrancesca,Ricci, Alfredo,Zwanenburg, Binne
, p. 3135 - 3143 (2007/10/03)
A series of enantiomerically pure aziridin-2-yl methanols have been synthesized from aziridine-2-carboxylic esters and have been tested as organocatalysts in Diels-Alder reactions and Friedel-Crafts alkylations of N-methyl-pyrrole and N-methyl-indole usin
Aza-Payne rearrangement of α,α-disubstituted-aziridinemethanols
Xichun, Feng,Guofu, Qiu,Shucai, Liang,Hanbing, Teng,Lamei, Wu,Xianming, Hu
, p. 1394 - 1401 (2007/10/03)
The aza-Payne rearrangement of activated N-Ts-α,α-disubstituted-aziridinemethanols, induced by NaOH in the mixed solvent tBuOH/H2O/THF (4:5:1) or NaH in a mixed solvent of THF/HMPA (10:1), as well as some N-Boc-α,α-disubstituted-azir
Synthesis and crystal structure of enantiopure N-tritylaziridin-2-yl-methanols from L-serine and L-threonine
Willems, Johannes G. H.,Hersmis, Marco C.,De Gelder, Rene,Smits, Jan M. M.,Hammink, Jeannet B.,Dommerholt, F. Jan,Thijs, Lambertus,Zwanenburg, Binne
, p. 963 - 967 (2007/10/03)
A convenient multigram 'one pot procedure' for the synthesis of methyl N-tritylaziridine-2-carboxylates 1 and 2, starting from the N-tritylmethyl esters of L-serine 9 and L-threonine 10 and using methanesulfonyl chloride and triethylamine, is described. T
Asymmetric Ketone Reduction using Chiral Oxazaborolidines derived from Aziridine Carbinols
Willems, Johannes G. H.,Dommerholt, F. Jan,Hammink, Jeannet B.,Vaarhorst, Ariaela M.,Thijs, Lambertus,Zwanenburg, Binne
, p. 603 - 606 (2007/10/02)
Asymmetric borane reduction of acetophenone using 1,3,2-oxazaborolidines derived from aziridine-2-tertiary alcohols 1 and 2 yielded the corresponding alcohol in high optical yields.The synthesis of the novel chiral catalysts 1 and 2 using D-and L-serine,
