167263-25-4Relevant academic research and scientific papers
Identification and chemical synthesis of MDL 105,212, a non-peptide tachykinin antagonist with high affinity for NK1 and NK2 receptors
Burkholder, Timothy P.,Kudlacz, Elizabeth M.,Le, Tieu-Binh,Knippenberg, Robert W.,Shatzer, Scott A.,Maynard, George D.,Webster, Mark E.,Horgan, Stephen W.
, p. 951 - 956 (2007/10/03)
We have synthesized and identified MDL 105,212, a non-peptide tachykinin receptor antagonist that has high affinity for human NK1 ((IC50 = 3.11 nM) and NK2 (IC50 = 8.40 nM) receptors. The chemical synthesis of M
