16727-28-9

Usage

Uses

Used in Analytical Chemistry:
8-Hydroxy-6-nitroquinoline is used as a fluorescence reagent for the analysis of metal ions, as it can form stable complexes with these metals, enhancing the detection and quantification of metal ions in various samples.
Used in Organic Synthesis:
In the field of organic synthesis, 8-hydroxy-6-nitroquinoline serves as a reactant in chemical reactions, contributing to the formation of various organic compounds, which can be further utilized in different applications.
Used in Pharmacology:
8-Hydroxy-6-nitroquinoline has been studied for its biological activities, including its potential antimicrobial and antitumor properties. Its ability to exhibit these properties makes it a candidate for further research and development in the pharmaceutical industry.
Used in the Synthesis of Organic Compounds:
8-Hydroxy-6-nitroquinoline is also utilized in the synthesis of various organic compounds, where it acts as a key intermediate in the production of different chemical entities, expanding its applications in the chemical and pharmaceutical sectors.

InChI:InChI=1/C9H6N2O3/c12-8-5-7(11(13)14)4-6-2-1-3-10-9(6)8/h1-5,12H

Upstream product

• 56-81-5 glycerol 
• 121-88-0 5-Nitro-2-aminophenol 
• 80912-11-4 8-methoxy-6-nitroquinoline 

Downstream Products

• 68748-35-6 6-amino-8-hydroxyquinoline 

Relevant academic research and scientific papers

A catalytic oxidation fragrant boron class compound preparing phenol method (by machine translation)

The invention discloses a method for catalytic oxidation of phenolic compounds fragrant boron class compound synthesis method, the flux in the solvent in the aqueous solution, under the action of alkali, adding hydrazine hydrate or acid hydrazides catalyst, catalytic oxidation fragrant boron class compound directly for the preparation of phenolic compound. The invention of the method of preparation of the phenol compound, the catalyst is a cheap hydrazine hydrate or hydrazine compound, the oxidizing agent is atmospheric pressure of air or oxygen, the reaction does not need good and activeness metal catalyst, is extensive and stable substrate, substrate-sensitive functional group compatibility good and wide range of application. In the optimized under the reaction conditions, the yield of the target product separation up to 99%. (by machine translation)

The Photo-induced Ring Expansion of Azido(methoxy)quinolines to Methoxypyridoazepines

The yield of 9-alkylamino-5H-pyridoazepines from the photo-induced ring-expansion of 8-azidoquinoline in primary amines are increased significantly by the presence of a 6-methoxy group, which also for the first time induces ring-expansion of the azide in secondary amines.Optimum conditions have been found for the ring-expansion of 8-azidoquinoline in methanol-potassium methoxide to give 9-methoxy-5H-pyridoazepine, and under the same conditions 8-azido-6-methoxy- and 6-azido-8-methoxy-quinoline ring-expand in excellent yield to the corresponding dimethoxypyridoazepines.