167305-85-3

Upstream product

• 167305-83-1 2-(acetylamino)-2-[4-(acetyloxy)butyl]propanedioic acid, diethyl ester 
• 167305-84-2 2-(Acetylamino)-6-hydroxyhexanoic acid 
• 38869-96-4 (3RS)-3-[N-(Benzyloxycarbonyl)amino]-2-oxo-tetrahydrothiophene 
• 13139-17-8 N-(Benzyloxycarbonyloxy)succinimide 
• 121895-18-9 (S)-2-amino-6-hydroxyhexanoic acid methyl ester hydrochloride 
• 167305-82-0 (S)-4-(acetylthio)-2-(benzyloxycarbonylamino)butanoic acid 

Downstream Products

• 229976-38-9 (4S,6S,9aS)-6-((S)-2-Mercapto-3-phenyl-propionylamino)-5-oxo-octahydro-9-thia-4a-aza-benzocycloheptene-4-carboxylic acid methyl ester 
• 167305-43-3 (3S,7S,11S)-1-aza-3-benzyloxycarbonylamino-11-methoxycarbonyl-2-oxo-6-thiabicyclo[5.4.0]undecane 
• 167304-98-5 [4S-(4α,7α,10aβ)]-4-amino-octahydro-5-oxo-7H-pyrido[2,1-b] [1,3]thiazepine-7-carboxylic acid, methyl ester 
• 167305-86-4 (S)-2-((S)-4-Acetylsulfanyl-2-benzyloxycarbonylamino-butyrylamino)-6-oxo-hexanoic acid methyl ester 

Relevant academic research and scientific papers

Dual metalloprotease inhibitors: Mercaptoacetyl-based fused heterocyclic dipeptide mimetics as inhibitors of angiotensin-converting enzyme and neutral endopeptidase

A series of 7,6- and 7,5-fused bicyclic thiazepinones and oxazepinones were generated and incorporated as conformationally restricted dipeptide surrogates in mercaptoacyl dipeptides. These compounds are potent inhibitors of angiotensin-converting enzyme (