167305-87-5Relevant academic research and scientific papers
Dual metalloprotease inhibitors: Mercaptoacetyl-based fused heterocyclic dipeptide mimetics as inhibitors of angiotensin-converting enzyme and neutral endopeptidase
Robl, Jeffrey A.,Sun, Chong-Qing,Stevenson, Jay,Ryono, Denis E.,Simpkins, Ligaya M.,Cimarusti, Maria P.,Dejneka, Tamara,Slusarchyk, William A.,Chao, Sam,Stratton, Leslie,Misra, Raj N.,Bednarz, Mark S.,Asaad, Magdi M.,Cheung, Hong Son,Abboa-Offei, Benoni E.,Smith, Patricia L.,Mathers, Parker D.,Fox, Maxine,Schaeffer, Thomas R.,Seymour, Andrea A.,Trippodo, Nick C.
, p. 1570 - 1577 (2007/10/03)
A series of 7,6- and 7,5-fused bicyclic thiazepinones and oxazepinones were generated and incorporated as conformationally restricted dipeptide surrogates in mercaptoacyl dipeptides. These compounds are potent inhibitors of angiotensin-converting enzyme (
