16735-69-6

Usage

Uses

Used in Pharmaceutical Industry:
2-Methylbenzyl isothiocyanate is used as an antimicrobial agent for its ability to inhibit the growth of various microorganisms, making it a potential candidate for treating infections and promoting overall health.
2-Methylbenzyl isothiocyanate is used as an anticancer agent for its potential to target and inhibit the growth of cancer cells, offering a promising therapeutic approach for cancer treatment.
2-Methylbenzyl isothiocyanate is used as an anti-inflammatory agent for its ability to reduce inflammation and alleviate symptoms associated with inflammatory conditions.
Used in Food Industry:
2-Methylbenzyl isothiocyanate is used as a flavoring agent for its strong and pungent taste, enhancing the flavor profiles of various food products.
2-Methylbenzyl isothiocyanate is used as a preservative for its ability to inhibit the growth of spoilage-causing microorganisms, extending the shelf life of food products.
Used in Agricultural Industry:
2-Methylbenzyl isothiocyanate is used as a natural pesticide for its antimicrobial properties, helping to protect crops from diseases and pests.
2-Methylbenzyl isothiocyanate is used as a growth promoter for its potential to stimulate plant growth and improve crop yields.

InChI:InChI=1/C9H9NS/c1-8-4-2-3-5-9(8)6-10-7-11/h2-5H,6H2,1H3

Upstream product

• 89-93-0 ortho-methylbenzylamine 
• 463-71-8 thiophosgene 
• 96989-50-3 di-2-pyridyl thionocarbonate 
• 102368-13-8 1,1'-Thiocarbonyldi-2(1H)-pyridone 

Downstream Products

• 65672-88-0 N-(2-methylbenzyl)-N'-phenylthiourea 
• 74788-34-4 (2-Methyl-benzyl)-[3-methyl-thiazolidin-(2Z)-ylidene]-amine 
• 72239-32-8 (2-Methyl-benzyl)-thiazolidin-(2Z)-ylidene-amine 
• 74548-54-2 N-<2-Hydroxy-aethyl>-N'-<2-methyl-benzyl>-thioharnstoff 
• 61290-69-5 1-(2-Hydroxy-ethyl)-1-methyl-3-(2-methyl-benzyl)-thiourea 

Relevant academic research and scientific papers

Differentiating Antiproliferative and Chemopreventive Modes of Activity for Electron-Deficient Aryl Isothiocyanates against Human MCF-7 Cells

The consumption of Brassica vegetables provides beneficial effects through organic isothiocyanates (ITCs), products of the enzymatic hydrolysis of glucosinolate secondary metabolites. The ITC l-sulforaphane (l-SFN) is the principle agent in broccoli that demonstrates several modes of anticancer action. While the anticancer properties of ITCs like l-SFN have been extensively studied and l-SFN has been the subject of multiple human clinical trials, the scope of this work has largely been limited to those derivatives found in nature. Previous studies have demonstrated that structural changes in an ITC can lead to marked differences in a compound's potency to 1) inhibit the growth of cancer cells, and 2) alter cellular transcriptional profiles. This study describes the preparation of a library of non-natural aryl ITCs and the development of a bifurcated screening approach to evaluate the dose- and time-dependence on antiproliferative and chemopreventive properties against human MCF-7 breast cancer cells. Antiproliferative effects were evaluated using a commercial MTS cell viability assay. Chemopreventive properties were evaluated using an antioxidant response element (ARE)-promoted luciferase reporter assay. The results of this study have led to the identification of 1) several key structure–activity relationships and 2) lead ITCs for continued development.

Characterization of the binding site of the histamine H3 receptor. 2. Synthesis, in vitro pharmacology, and QSAR of a series of monosubstituted benzyl analogues of thioperamide

A series of monosubstituted benzyl analogues of the histamine H3 receptor antagonist thioperamide were synthesized and evaluated for their histamine H3 receptor activity on the guinea pig jejunum. Incorporation of Cl, Br, and I at th

Synthesis and Octopaminergic Agonist Activity of 2-(Substituted benzylamino)-2-thiazolines

2-(Substituted benzylamino)-2-thiazolines (SBAT) were synthesized by a hydrochloric acid-catalyzed cyclization of the corresponding thioureas, using a reaction of 2-methylthio-2-thiazoline with substituted benzylamines or by alkylating 2-amino-2-thiazoline. 2-(Alkylthio)-2-thiazolines were obtained by alkylating 2-mercaptothiazoline.Most of the SBAT compounds activated adenylate cyclase in homogenates of cockroach ventral nerve cords; the effect of introducing substituents at the phenyl of the SBAT compounds on octopaminergic agonist activity was not significant. 2--2-thiazolines and 2-(alkylthio)-2-thiazolines were not significant octopaminergic agonists.Washing removed nearly all of the activity of one of the SBAT compounds, suggesting that the SBAT compounds bound reversibly to the octopaminergic receptor.