167364-29-6 Usage
Chemical class
spiro compounds
Type of compound
tropinone derivative
Structure
spiro ring consisting of a six-membered saturated carbon ring and an azaspiro[4.5]decan ring
Pharmacological effects
potential cholinergic activity
Receptors
acts as an agonist at muscarinic acetylcholine receptors, specifically the M2 and M4 subtypes
Therapeutic applications
potential use in conditions such as Alzheimer's disease and schizophrenia
Research use
utilized as a tool compound to study the effects of cholinergic stimulation on various physiological processes.
Check Digit Verification of cas no
The CAS Registry Mumber 167364-29-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,7,3,6 and 4 respectively; the second part has 2 digits, 2 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 167364-29:
(8*1)+(7*6)+(6*7)+(5*3)+(4*6)+(3*4)+(2*2)+(1*9)=156
156 % 10 = 6
So 167364-29-6 is a valid CAS Registry Number.
InChI:InChI=1/C8H13NO2/c10-7-1-2-8(11-7)3-5-9-6-4-8/h9H,1-6H2
167364-29-6Relevant academic research and scientific papers
4(SPIROPIPERIDINYL)METHYL SUBSTITUTED PYRROLIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY
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Page 34, (2010/02/07)
3-Substituted pyrrolidines having a spiropiperidinylmethyl substituent on the 4-position of the ring are useful as modulators of chemokine receptor activity. In particular, these compounds are useful as modulators of the chemokine receptors CCR-3 and/or CCR-5.
4,4-Disubstituted cyclohexylamine NK1 receptor antagonists II
Cooper, Laura C.,Carlson, Emma J.,Castro, Jose L.,Chicchi, Gary G.,Dinnell, Kevin,Di Salvo, Jerry,Elliott, Jason M.,Hollingworth, Gregory J.,Kurtz, Marc M.,Ridgill, Mark P.,Rycroft, Wayne,Tsao, Kwei-Lan,Swain, Christopher J.
, p. 1759 - 1762 (2007/10/03)
A series of novel 4,4-disubstituted cyclohexylamines as NK1 receptor antagonists is described: modifications to the amine moiety retain NK1 receptor binding affinity whilst disrupting IKr affinity.
