167380-79-2Relevant academic research and scientific papers
Synthesis of Novel 5-Hydroxy-3-alkoxy- And 5-Hydroxy-3-alkylthio-indole-2-carboxamides
Unangst, Paul C.,Connor, David T.,Miller, Steven R.
, p. 1627 - 1630 (1996)
The preparation of several novel 5-hydroxyindole-2-carboxamides is described. A 5-benzyloxyindole ester was elaborated to the 3-bromo, 3-hydroxy, and 3-alkoxy ester intermediates followed by conversion to the amide and debenzylation. A related 5-acetyloxy
Indole-2-carboxamides as inhibitors of cell adhesion
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, (2008/06/13)
3-Substituted-indole-2-carboxamides are described as agents which inhibit leukocyte adherence to vascular endothelium and, as such, are effective therapeutic agents for treating inflammatory diseases. Certain of these compounds are novel and methods of ma
