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4-Cyclopropylbenzene-1-sulfonyl chloride is a chemical compound that belongs to the class of organic compounds known as benzenesulfonyl chlorides. It is characterized by a benzene ring (a hexagonal ring of six carbon atoms) substituted by a cyclopropyl group (a three-carbon ring) at one position and a sulfonyl chloride group (containing sulfur, oxygen, and chlorine atoms) at another position. The presence of a sulfonyl chloride group makes it an important chemical in the synthesis of various sulfonamide and sulfonyl compounds. It is often used in chemical reactions as a sulfonylating agent.

167404-32-2

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167404-32-2 Usage

Uses

Used in Pharmaceutical Industry:
4-Cyclopropylbenzene-1-sulfonyl chloride is used as a key intermediate in the synthesis of various pharmaceutical compounds, particularly sulfonamide drugs. Its sulfonyl chloride group allows for the formation of sulfonamide linkages, which are essential for the development of certain medications.
Used in Chemical Synthesis:
4-Cyclopropylbenzene-1-sulfonyl chloride is used as a sulfonylating agent in the synthesis of a wide range of organic compounds. Its reactivity with various functional groups enables the formation of new chemical bonds and the creation of diverse molecular structures.
Used in Research and Development:
4-Cyclopropylbenzene-1-sulfonyl chloride is used as a research compound in academic and industrial laboratories. Its unique structure and reactivity make it a valuable tool for studying the properties and behavior of benzenesulfonyl chlorides and related compounds.

Check Digit Verification of cas no

The CAS Registry Mumber 167404-32-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,7,4,0 and 4 respectively; the second part has 2 digits, 3 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 167404-32:
(8*1)+(7*6)+(6*7)+(5*4)+(4*0)+(3*4)+(2*3)+(1*2)=132
132 % 10 = 2
So 167404-32-2 is a valid CAS Registry Number.

167404-32-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-Cyclopropylbenzene-1-sulfonyl chloride

1.2 Other means of identification

Product number -
Other names 4-Cyclopropylbenzenesulfonyl chloride

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:167404-32-2 SDS

167404-32-2Relevant academic research and scientific papers

CHEMICAL COMPOUNDS

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Paragraph 0179-0181, (2021/04/02)

The present disclosure describes novel compounds, or their pharmaceutically acceptable salts, pharmaceutical compositions containing them, and their medical uses. The compounds of the disclosure have activity as Janus kinase (JAK) inhibitors and are useful in the treatment or control of inflammation, auto-immune diseases, cancer, and other disorders and indications where modulation of JAK would be desirable. Also described herein are methods of treating inflammation, auto-immune diseases, cancer, and other conditions susceptible to inhibition of JAK by administering a compound herein described.

Optimization of triaryl bis-sulfones as cannabinoid-2 receptor ligands

Lavey, Brian J.,Kozlowski, Joseph A.,Shankar, Bandarpalle B.,Spitler, James M.,Zhou, Guowei,Yang, De-Yi,Shu, Youheng,Wong, Michael K.C.,Wong, Shing-Chun,Shih, Neng-Yang,Wu, Jie,McCombie, Stuart W.,Rizvi, Razia,Wolin, Ronald L.,Lunn, Charles A.

, p. 3760 - 3764 (2008/02/12)

Structure-activity relationship on our recently reported triaryl bis-sulfone class of cannabinoid-2 (CB2) receptor selective inverse agonists was explored. Modifications to the methane sulfonamide, substitutions to B and C phenyl rings, and replacements o

CANNABINOID RECEPTOR LIGANDS

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Page 38-39, (2008/06/13)

A compound of the formula (I) or a pharmaceutically acceptable salt or solvate thereof, wherein:R1, R2, L1, L2, M1, M2, n, p, q, A, D, X, Y and Z are as described in the specification; phar

Cannabinoid receptor ligands

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Page 48, (2008/06/13)

The invention relates to compounds of the formula a prodrug thereof, or a pharmaceutically acceptable salt, solvate or stereoisomer of the compound or of said prodrug; which exhibit anti-inflammatory and immunodulatory activity. Also disclosed are pharmac

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