167416-28-6 Usage
Reaction
Ligand for Pd-catalyzed C-N cross-coupling
Ligand for Rh-catalyzed C-N cross-coupling
Ligand for Pd-catalyzed asymmetric synthesis of (S)-QUINAP via dynamic kinetic resolution
Ligand for Ni-catalyzed monoarylation of ammonia
General Description
sold in collaboration with Solvias AG
Check Digit Verification of cas no
The CAS Registry Mumber 167416-28-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,7,4,1 and 6 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 167416-28:
(8*1)+(7*6)+(6*7)+(5*4)+(4*1)+(3*6)+(2*2)+(1*8)=146
146 % 10 = 6
So 167416-28-6 is a valid CAS Registry Number.
InChI:InChI=1/C31H51P2.C5H5.Fe/c1-25(32(26-15-6-2-7-16-26)27-17-8-3-9-18-27)30-23-14-24-31(30)33(28-19-10-4-11-20-28)29-21-12-5-13-22-29;1-2-4-5-3-1;/h14,23-29H,2-13,15-22H2,1H3;1-5H;/t25-;;/m1../s1
167416-28-6Relevant articles and documents
Rhodium-Catalyzed Asymmetric Allylation of Malononitriles as Masked Acyl Cyanide with Allenes: Efficient Access to β,γ-Unsaturated Carbonyls
Grugel, Christian P.,Breit, Bernhard
supporting information, p. 15223 - 15226 (2018/09/25)
A rhodium-catalyzed regio- and enantioselective intermolecular allylation of malononitriles as masked acyl cyanides (MAC) with terminal and symmetrical internal allenes is reported. A RhI/Josiphos catalytic system combined with subsequent oxidative degradation of the primary adducts enables a straightforward access to α-branched, β,γ-unsaturated carbonyl compounds. The present protocol exhibits perfect atom economy in the allylation step and is characterized by a great functional group compatibility. Furthermore, the use of α-substituted malononitriles allowed for the construction of all-carbon quaternary centers.
