167487-83-4 Usage
General Description
1H-Benzimidazole-4-carboxylic acid, ethyl ester is a chemical compound with the molecular formula C11H11N3O2. It is commonly used in the pharmaceutical industry as a building block in the synthesis of various drugs. It has been found to exhibit antimicrobial, antiviral, and antifungal properties, making it a valuable component in the development of new medications. The ethyl ester form of this compound also makes it useful as a solvent or carrier for other active ingredients in drug formulations. Additionally, research has shown that 1H-Benzimidazole-4-carboxylic acid, ethyl ester may have potential anti-inflammatory and anticancer properties, which further enhances its importance in biomedical research and drug development efforts.
Check Digit Verification of cas no
The CAS Registry Mumber 167487-83-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,7,4,8 and 7 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 167487-83:
(8*1)+(7*6)+(6*7)+(5*4)+(4*8)+(3*7)+(2*8)+(1*3)=184
184 % 10 = 4
So 167487-83-4 is a valid CAS Registry Number.
167487-83-4Relevant articles and documents
A facile one-pot synthesis of benzimidazoles from 2-nitroanilines by reductive cyclization
Liu, Zheng,Li, Haihong,Zhao, Qingjie,Shen, Jingshan
scheme or table, p. 1907 - 1911 (2009/04/06)
A facile one-pot process to prepare benzimidazole derivatives is described. Reductive cyclization of a serial of 2-nitroanilines with orthoesters in the presence of Pd/C in methanol at room temperature, which is promoted by a catalytic amount of acetic acid, affords the corresponding benzimidazole derivatives in high yields.