65658-13-1

Basic information

• Product Name: 1H-Benzimidazole-4-methanol(9CI)
• Synonyms: 1H-Benzimidazole-4-methanol(9CI);(1H-benzo[d]imidazol-4-yl)methanol;(1H-Benzimidazol-4-yl)methanol;4-(Hydroxymethyl)-1H-benzimidazole;1H-1,3-benzodiazol-4-ylmethanol;1H-Benzimidazole-7-methanol;(1H-Benzo[d]imidazol-4-yl)
• CAS NO: 65658-13-1
• Molecular Formula: C8H8N2O
• Molecular Weight: 148.16
• Product Categories: BENZIMIDAZOLE
• Mol File: 65658-13-1.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 469.534°C at 760 mmHg
• Flash Point: 237.766°C
• Appearance: /
• Density: 1.36g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.721
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 12.51±0.30(Predicted)
• CAS DataBase Reference: 1H-Benzimidazole-4-methanol(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Benzimidazole-4-methanol(9CI)(65658-13-1)
• EPA Substance Registry System: 1H-Benzimidazole-4-methanol(9CI)(65658-13-1)

Safety Data

• Hazardous Substances Data: 65658-13-1(Hazardous Substances Data)

Usage

General Description

1H-Benzimidazole-4-methanol(9CI) is a chemical compound with the molecular formula C8H8N2O. It is a white solid substance that is used in various pharmaceutical and chemical applications. 1H-Benzimidazole-4-methanol(9CI) is a derivative of benzimidazole and contains a hydroxyl group attached to the fourth carbon atom. It is considered to be a versatile building block in organic synthesis and is used in the production of various drugs and other fine chemicals. Additionally, 1H-Benzimidazole-4-methanol(9CI) has been studied for its potential biological activities and is considered to have potential therapeutic applications.

InChI:InChI=1/C8H8N2O/c11-4-6-2-1-3-7-8(6)10-5-9-7/h1-3,5,11H,4H2,(H,9,10)

Upstream product

• 312600-95-6 1H-benzo[d]imidazole-4-carboxylic acid hydrochloride 
• 603-81-6 2,3-diaminobenzoic acid 
• 606-18-8 3-nitroanthranilic acid 
• 77326-45-5 2-carbamoyl-3-nitrobenzoic acid 
• 641-70-3 3-nitrophthalic acid anhydride 
• 37619-25-3 methyl 1H-benzo[d]imidazole-4-carboxylate 
• 46006-36-4 benzimidazole-4-carboxylic acid 
• 167487-83-4 ethyl 1H-1,3-benzodiazole-4-carboxylate 

Downstream Products

• 144876-36-8 1H-benzo[d]imidazole-4-carbaldehyde 
• 132873-77-9 4-(bromomethyl)benzimidazole-1-carboxylic acid,1,1-dimethylethyl ester 
• 1352874-02-2 N-{4'-[3-(1H-Benzoimidazol-4-ylmethyl)-6-fluoro-2-imino-2,3-dihydro-benzoimidazol-1-yl]-5-chloro-biphenyl-2-yl}-acetamide 

Relevant articles and documents

BICYCLIC HETEROARYL DERIVATIVES AS ECTONUCLEOTIDE PYROPHOSPHATASE PHOSPHODIESTERASE 1 INHIBITORS

The present disclosure provides certain bicyclic heteroaryl compounds that inhibit ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1) enzymatic activity and are therefore useful for the treatment of diseases and conditions modulated at least in part by ENPP1. In some embodiments, the bicyclic heteroaryl compounds includes those of Formula (I). Also provided herein are pharmaceutical compositions containing such compounds and processes for preparing such compounds.

TRIAZOLOPYRIDINE AND TRIAZOLOPYRIMIDINE INHIBITORS OF MYELOPEROXIDASE

The present invention provides compounds of Formula (I): wherein A and R1 are each as defined in the specification, and compositions comprising any of such novel compounds. These compounds are myeloperoxidase (MPO) inhibitors and/or eosinophil peroxidase (EPX) inhibitors, which may be used as medicaments.

PIPERIDINYL SUBSTITUTED 1,3-DIHYDRO-BENZOIMIDAZOL-2-YLIDENEAMINE DERIVATIVES

The invention relates to new derivatives of formula (I) wherein the substituents are as defined in the specification; to processes for the preparation of such derivatives; pharmaceutical compositions comprising such derivatives; such derivatives as a medicament; such derivatives for the treatment of one or more IGF-1R mediated disorders or diseases