1675221-59-6

Basic information

• Product Name: Azilsartan Impurity
• Synonyms: 4'-((2-ethoxy-7-(methoxycarbonyl)-1H-benzo[d]imidazol-1-yl)methyl)-[1,1'-biphenyl]-2-carboxylic acid;Azilsartan Impurity 20
• CAS NO: 1675221-59-6
• Molecular Formula: C25H22N2O5
• Molecular Weight: 430.45
• Mol File: 1675221-59-6.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 627.7±65.0 °C(Predicted)
• Appearance: /
• Density: 1.26±0.1 g/cm3(Predicted)
• PKA: 3.82±0.36(Predicted)
• CAS DataBase Reference: Azilsartan Impurity(CAS DataBase Reference)
• NIST Chemistry Reference: Azilsartan Impurity(1675221-59-6)
• EPA Substance Registry System: Azilsartan Impurity(1675221-59-6)

Safety Data

• Hazardous Substances Data: 1675221-59-6(Hazardous Substances Data)

Upstream product

• 139481-44-0 methyl 1-[(2'-cyanobiphenyl-4-yl)methyl]-2-ethoxy-benzimidazole-7-carboxylate 

Relevant articles and documents

Commercial synthesis of azilsartan kamedoxomil: An angiotensin II receptor blocker

A commercially viable process for the preparation of azilsartan kamedoxomil, an angiotensin II receptor blocker, has been developed. The present work describes the novel synthesis of azilsartan medoxomil from amidoxime methyl ester. The present work also describes the improved synthesis of amidoxime methyl ester and azilsartan kamedoxomil. This process features a high overall yield (36%) with 99.52% HPLC purity.