16754-39-5

Usage

Uses

Used in Organic Synthesis:
Carbamic acid 2-propynyl ester is used as a reagent in organic synthesis for its ability to react with various nucleophiles, facilitating the formation of new chemical bonds and structures.
Used in Plastics Production:
In the plastics industry, carbamic acid 2-propynyl ester is used as a key intermediate in the production process, contributing to the development of specific plastic materials with desired properties.
Used in Pharmaceutical Industry:
Carbamic acid 2-propynyl ester is used as an intermediate in the synthesis of pharmaceuticals, playing a crucial role in the creation of various medicinal compounds.
Used in Agricultural Chemicals:
Carbamic acid 2-propynyl ester is utilized in the production of agricultural chemicals, including herbicides and insecticides, where its reactivity and intermediate properties are harnessed to create effective products for pest and weed control.
Used in Synthesis of Heterocyclic Compounds:
Carbamic acid 2-propynyl ester is used as a key intermediate in the synthesis of various heterocyclic compounds, which are important in the development of complex organic molecules with diverse applications.
Safety Precautions:
As a volatile and potentially hazardous chemical, proper handling and safety precautions are necessary when working with carbamic acid 2-propynyl ester to prevent accidents and ensure the safety of personnel and the environment.

InChI:InChI=1/C4H5NO2/c1-2-3-7-4(5)6/h1H,3H2,(H2,5,6)

Upstream product

• 75-44-5 phosgene 
• 107-19-7 propargyl alcohol 
• 57-13-6 urea 
• 3019-71-4 Trichloroacetyl isocyanate 
• 143-33-9 sodium cyanide 

Downstream Products

• 647028-91-9 Carbamic acid 4-hydroxy-6-[2-((2S,3R)-3-iodomethyl-1-trityl-aziridin-2-yl)-oxazol-5-yl]-hex-2-ynyl ester 
• 41142-35-2 (2-Chloro-5-trifluoromethyl-benzenesulfonyl)-prop-2-ynyloxycarbonylamino-acetic acid 

Relevant academic research and scientific papers

Enantioselective Synthesis of 3-Heterosubstituted-2-amino-1-ols by Sequential Metal-Free Diene Aziridination/Kinetic Resolution

A general protocol for the enantioselective synthesis of 3-heterosubstituted-2-amino-1-ols was developed based on metal- free intramolecular regio- and stereoselective diene aziridination and regioselective opening. Kinetic resolution of the resulting (1′-NR1R2 and 1′-SR)-4-oxazolidinones was performed using ABCs organocatalysts, expanding the application of this methodology.

Enantioselective Synthesis of Aminodiols by Sequential Rhodium-Catalysed Oxyamination/Kinetic Resolution: Expanding the Substrate Scope of Amidine-Based Catalysis

Regio- and stereoselective oxyamination of dienes through a tandem rhodium-catalysed aziridination–nucleophilic opening affords racemic oxazolidinone derivatives, which undergo a kinetic resolution acylation process with amidine-based catalysts (ABCs) to achieve s values of up to 117. This protocol was applied to the enantioselective synthesis of sphingosine.