167645-07-0

Upstream product

• 167645-02-5 2-Bromo-1-[7-(2-fluoro-benzoyl)-2-methyl-2,3-dihydro-indol-1-yl]-ethanone 
• 6872-06-6 2-methyl indoline 
• 167645-01-4 (2-Fluoro-phenyl)-(2-methyl-2,3-dihydro-1H-indol-7-yl)-methanone 
• 394-47-8 2-fluorobenzonitrile 
• 108-24-7 acetic anhydride 
• 167645-03-6 1-(2-Fluoro-phenyl)-6-methyl-2-oxy-6,7-dihydro-3H-[1,4]diazepino[6,7,1-hi]indol-4-one 

Downstream Products

• 167645-14-9 3-Amino-1-(2-fluoro-phenyl)-6-methyl-6,7-dihydro-3H-[1,4]diazepino[6,7,1-hi]indol-4-one 
• 167645-09-2 1-(2-Fluoro-phenyl)-3-hydroxy-6-methyl-6,7-dihydro-3H-[1,4]diazepino[6,7,1-hi]indol-4-one 

Relevant academic research and scientific papers

Studies on a novel, potent and orally effective cholecystokinin A antagonist, FK-480. Synthesis and structure-activity relationships of FK-480 and related compounds

We prepared various novel tricyclic 1,4-benzodiazepine derivatives as cholecystokinin (CCK) A antagonists, which were evaluated preliminarily for inhibition of 125I-CCK-8 binding to rat pancreatic membranes in vitro and inhibiting effect on CCK