16768-43-7 Usage
Description
2,4-DICHLORO-5-(CHLOROMETHYL)-6-METHYLPYRIMIDINE is a chemical compound belonging to the pyrimidine group. It is a derivative of pyrimidine with two chlorine atoms attached at the 2nd and 4th positions, a chloromethyl group attached at the 5th position, and a methyl group attached to the 6th position. This versatile compound is known for its diverse properties and biological activities.
Used in Pharmaceutical Industry:
2,4-DICHLORO-5-(CHLOROMETHYL)-6-METHYLPYRIMIDINE is used as a key intermediate in the synthesis of various pharmaceuticals. Its unique structure allows it to be incorporated into the development of new drugs, enhancing their therapeutic properties and effectiveness in treating a range of medical conditions.
Used in Agrochemical Industry:
In the agrochemical sector, 2,4-DICHLORO-5-(CHLOROMETHYL)-6-METHYLPYRIMIDINE serves as a crucial building block for the creation of novel agrochemicals. Its incorporation into these products can lead to improved pest control, crop protection, and overall agricultural productivity.
Used in Organic Synthesis:
2,4-DICHLORO-5-(CHLOROMETHYL)-6-METHYLPYRIMIDINE is utilized as a versatile building block in organic synthesis. It enables the development of new chemical compounds for a variety of industrial and research applications, contributing to advancements in material science, chemical engineering, and other related fields.
Check Digit Verification of cas no
The CAS Registry Mumber 16768-43-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,6,7,6 and 8 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 16768-43:
(7*1)+(6*6)+(5*7)+(4*6)+(3*8)+(2*4)+(1*3)=137
137 % 10 = 7
So 16768-43-7 is a valid CAS Registry Number.
16768-43-7Relevant articles and documents
5-Ethylthiomethyl- and 5-Ethylsulfonylmethylpyrimidines
Eichberger, Guenter,Hayden, Walter,Schwarz, Wolfgang,Griengl, Herfried
, p. 385 - 392 (1986)
In 2,4-dichloro-5-ethylthiomethylpyrimidines 3a,b and in (2,4-dichloro-5-pyrimidinylmethyl)ethyl sulfones 5a,b, resp., by reaction with ammonia, diethylamine, isopropylamine, sodium methanolate and sodium ethylthiolate, resp., the halogen atoms have been substituted by amino, methoxy or ethylthio groups, resp., and thus the compounds 4a-4r and 5c-5f have been obtained.Keywords: Halogen exchange, in pyrimidines; Pyrimidines, 5-ethylsulfonyl-methyl-; Pyrimidines, 5-ethylthiomethyl-
Regioselective synthesis of new 5H,10H-dipyrimido[2,1-b:4′,5′-d][1,3]thiazine: a combined experimental and computational study
Afrough, Toktam,Bakavoli, Mehdi,Eshghi, Hossein,Tajabadi, Javad,Mague, Joel
, p. 265 - 276 (2019/02/13)
Several derivatives of the novel tricyclic system ‘dipyrimido[2,1-b:4′,5′-d][1,3]thiazine’ were synthesized via inter- and intramolecular heterocyclization of 2,4-dichloro-5-(chloromethyl)-6-methylpyrimidine and 6-amino-4-aryl-2-thioxo-1,2,3,4-tetrahydrop
Regioselective synthesis of new 5-methyl-5H-pyrimido[4′,5′:4,5][1,3]thiazino [3,2-a]perimidines
Firoozi, Neda,Bakavoli, Mehdi,Eshghi, Hossein,Ramezanian, Navid
, p. 488 - 495 (2017/09/27)
A convenient and efficient regioselective synthesis of new pyrimido[4′,5′:4,5] [1,3]thiazino[3,2-a]perimidines is described through intermolecular heterocyclization of 2,4-dichloro-5-(chloromethyl)-6-methylpyrimidine and 1H-perimidine-2(3H)-thione in short reaction times under mild conditions.
