167700-34-7Relevant academic research and scientific papers
Red light-triggered photoreduction on a nucleic acid template
Deussner-Helfmann, Nina,Duchstein, Patrick,Dutta, Subrata,Heilemann, Mike,Kn?r, Günther,Mokhir, Andriy,Rühle, Jennifer,Schikora, Margot,Zahn, Dirk,Zatsepin, Timofei
, p. 10026 - 10029 (2020)
Conjugate Sn(iv)(pyropheophorbide a)dichloride-(peptide nucleic acid) catalyzes reduction of azobenzene derivatives in the presence of complementary nucleic acid (NA) upon irridiation with red light (660 nm). This is the first red light-induced NA-templat
A new 9-alkyladenine-cyclic methylglyoxal diadduct activates wt- and F508del-cystic fibrosis transmembrane conductance regulator (CFTR) in vitro and in vivo
Boucherle, Benjamin,Bertrand, Johanna,Maurin, Bruno,Renard, Brice-Lo?c,Fortuné, Antoine,Tremblier, Brice,Becq, Frédéric,Norez, Caroline,Décout, Jean-Luc
, p. 455 - 465 (2014/07/21)
Cystic fibrosis transmembrane conductance regulator (CFTR) is the main chloride channel present in the apical membrane of epithelial cells and the F508 deletion (F508del-CFTR) in the CF gene is the most common cystic fibrosis-causing mutation. In the sear
Synthesis of Linear and Tripoidal Oligo(phenylene ethynylene)-Based Building Blocks for Application in Modular DNA-Programmed Assembly
Nielsen, Morten,Thomsen, Anne H.,Clo, Emiliano,Kirpekar, Finn,Gothelf, Kurt V.
, p. 2240 - 2250 (2007/10/03)
Rigid linear and tripoidal organic modules based on the oligo(phenylene ethynylene) backbone having salicylaldehyde-derived termini are synthesized. A highly functionalized 5-iodosalicyl aldehyde was prepared and coupled to each ethynyl group of 1,4-diethynylbenzene or 1,3,5-triethynylbenzene in Sonogashira couplings. The two or three termini of the compounds are functionalized for incorporation in linear and branched oligonucleotide strands. For the linear module (LM), the two termini are equipped with amide spacers, and one of these was functionalized with a DMTr (dimethoxytrityl)-protected hydroxy group and the other with a phosphoramidite. One of the tripoidal modules is prepared with DMTr groups in two of its three termini. A tripoidal module is also synthesized with three different groups on its hydroxy termini: a phosphoramidite, a DMTr group, and an Fmoc group. Extended studies have shown that these rigid linear and tripoidal organic modules can be incorporated into short oligonucleotides. Several of these modules can be applied for DNA-directed assembly and covalent coupling into structures of predetermined connectivity. Such structures have potential application for molecular electronics and nanotechnology.
SPECIFICALLY CLEAVABLE OLIGODEOXYRIBONUCLEOTIDES FOR REVERSIBLE IMMOBILIZATION OF DNA
Shchepinov, M. S.,Esipov, D. S.,Korobko, V. G.,Dobrynin, V. N.
, p. 520 - 528 (2007/10/02)
Carriers for the reversible immobilization of DNA were prepared using streptavidin-coated TSK gel with surface binding capacities of 50-70 nmoles of oligonucleotide per g of dry carrier, with oligonucleotides bearing biotin residues at the 5'- and 3'-ends
