167702-98-9

Upstream product

• 3031-68-3 Hexa-2,4-diyne-1,6-diol 
• 152844-32-1 (2R,3R)-6-O-silyl-2,3-epoxy-hex-4-yn-1,6-diol 
• 152844-31-0 2E-6-O-silyl-hexen-4-yn-1,6-diol 
• 152844-30-9 6-O-silyl-hex-2,4-diyn-1,6-diol 
• 67373-56-2 chlorodimethyl(1,1,2-trimethylpropyl)silane 
• 98-59-9 p-toluenesulfonyl chloride 
• 167702-97-8 (2R,3S)-6-O--3-methylthio-hex-4-yn-1,2,6-triol 

Downstream Products

• 167392-37-2 (4S,5R)-4-methylthio-6-O-(4-methylbenzenesulfonyl)-hex-2-yn-1,5,6-triol 

Relevant academic research and scientific papers

Synthesis of 2,6-Dideoxy-4-S-Methyl-4-Thio-D-ribo-Hexopyranose, A Component of the Esperamicin Oligosaccharide

Two synthetic approaches to 2,6-dideoxy-4-S-methyl-4-thio-D-ribo pyranose, a component of the oligosaccharide of esperamicins are described.An asymmetric synthesis, starting from the propargylic alcohol dimer, relies on the Sharpless asymmetric epoxidation and the regioselective opening of epoxy alcohols.The other synthesis is based on stereocontrolled transformations of a readily available sugar precursor, D-galactose.

Two syntheses of 2,4,6-trideoxy-4-methylthio-D-ribo-pyranose

Two synthesis of 2,4,6-trideoxy-4-methylthio-D-ribo-pyranose, a component of the oligosaccharide of esperamicins are described: an asymmetric synthesis starting from the propargylic alcohol dimer and the stereocontrolled transformation of D-fucose.