167754-55-4Relevant academic research and scientific papers
Synthesis of aza analogues of the anticancer agent batracylin
Martínez-Viturro, Carlos M.,Domínguez, Domingo
, p. 4707 - 4710 (2008/03/13)
Three series of pyrido-fused pyrimido[2,1-a]isoindol-7-ones were prepared from readily available (aminopyridinyl)(aryl)methanones by reduction followed by a Mitsunobu reaction with phthalimide and acid-catalysed cyclodehydration. This approach provides a wide variety of aza analogues of the antitumour agent batracylin.
Synthesis and structure-activity relationship studies on a novel series of naphthylidinoylureas as inhibitors of acyl-CoA:cholesterol O-acyltransferase (ACAT)
Ohnuma, Satoshi,Muraoka, Masami,Ioriya, Katsuhisa,Ohashi, Naohito
, p. 1309 - 1311 (2007/10/03)
The synthesis and structure-activity relationships of N-phenyl-N′-[3- (4-phenylnaphthylidinoyl)]urea derivatives 3 as a novel structural class of potent ACAT inhibitors is described. A 3-methoxy group substituted on the naphthylidinone 4-phenyl ring, toge
