16777-87-0

Basic information

• Product Name: 3,3-DIETHOXY-1-PROPANOL
• Synonyms: 3,3-DIETHOXY-1-PROPANOL;3,3-diethoxypropanol;3,3-Diethoxy-propan-1-ol;3,3-Diethoxy-1-propanol 98%
• CAS NO: 16777-87-0
• Molecular Formula: C₇H₁₆O₃
• Molecular Weight: 148.2
• Product Categories: Alcohols;C7 to C8;Oxygen Compounds;Building Blocks;C7 to C8;Chemical Synthesis;Organic Building Blocks;Oxygen Compounds
• Mol File: 16777-87-0.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 90-93 °C14 mm Hg(lit.)
• Flash Point: 196 °F
• Appearance: Clear colorless/Liquid
• Density: 0.941 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.149mmHg at 25°C
• Refractive Index: n20/D 1.421(lit.)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• Solubility: Chloroform (Slightly), Methanol (Slightly)
• PKA: 15.05±0.10(Predicted)
• CAS DataBase Reference: 3,3-DIETHOXY-1-PROPANOL(CAS DataBase Reference)
• NIST Chemistry Reference: 3,3-DIETHOXY-1-PROPANOL(16777-87-0)
• EPA Substance Registry System: 3,3-DIETHOXY-1-PROPANOL(16777-87-0)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 16777-87-0(Hazardous Substances Data)

Usage

Uses

3,3-Diethoxy-1-propanol was used in the synthesis of α-acetal-poly(ethylene glycol) via reaction with potassium napthalide and ethylene oxide inside an UniLab Glovebox.

InChI:InChI=1/C7H16O3/c1-3-9-7(5-6-8)10-4-2/h7-8H,3-6H2,1-2H3

Upstream product

• 2134-29-4 3-Hydroxypropanal 
• 122-51-0 orthoformic acid triethyl ester 
• 3054-95-3 acrylaldehyde diethyl acetal 
• 35573-93-4 3-chloro-1,1-diethoxy-propane 
• 78314-63-3 3-benzyloxypropionaldehyde diethyl acetal 
• 10601-80-6 ethyl 3,3-diethoxypropanoate 

Downstream Products

• 2134-29-4 3-Hydroxypropanal 
• 62592-78-3 3-(2-tetrahydropyranyloxy)propanal 
• 6367-37-9 3,3-diethoxypropanal 
• 19060-08-3 3-ethoxyacrolein 
• 161690-39-7 Dibenzyl 3,7-diethyl-5-(2-hydroxyethyl)-2,8-dimethyldihydrodipyrrin-1,9-dicarboxylate 
• 131543-46-9 Glyoxal 
• 400835-51-0 (2R,3S,4S,5R,6R)-3-Benzyloxy-2-(3,3-diethoxy-propoxy)-6-isobutoxymethyl-4,5-dimethoxy-tetrahydro-pyran 

Relevant articles and documents

Method For Manufacturing Hydroxyl Group-containing Acetal Compound

A method for manufacturing an acetal compound represented by the formula [1] in which the steps (A) to (D) as defined herein are performed sequentially, and an acetal compound of the formula [1] which is produced by the method: wherein n is 0 or 1 provided that R1 groups may be bonded or may not be bonded to each other when n is 0; R1 is an alkyl group having 1 or 2 carbon atoms or an alkylene group having 1 or 2 carbon atoms and the R1 groups may be same or different from each other; and R2 is an alkylene group having 1 or 6 carbon atoms.

TOTAL SYNTHESIS OF MAYTANSINOIDS. APPROACH TO 4,6-BISDEMETHYLMAYTANSINE AND 4-DEMETHYLMAYTANSINE

A convergent strategy was elaborated to synthesize maytansine 1 and maytansinoids modified on the carbon skeleton, especially 4-demethylmaytansine 2, 6-demethylmaytansine 3, 4,6-bisdemethylmaytansine 4.In this paper, the feasibility of the project was verified by the preparation of key intermediates for the synthesis of 4,6-bisdemethylmaytansine and 6-demethylmaytansine.The C-1-N open chain compound 18 in the 4,6-bisdemethyl series was obtained.

Thiazolidinylethylchlorocarbonates

This invention relates to 2-(thiazolidin-2'-yl) ethylchlorocarbonates useful as intermediates in the synthesis of photographic image dye-providing materials and to their preparation by the reaction of the appropriate 2-(2'-hydroxyethyl)-thiazolidine with phosgene under certain conditions.