1678-49-5Relevant articles and documents
An one-pot two-step automated synthesis of [18F]T807 injection, its biodistribution in mice and monkeys, and a preliminary study in humans
Huang, Ya-Yao,Chiu, Ming-Jang,Yen, Ruoh-Fang,Tsai, Chia-Ling,Hsieh, Hao-Yu,Chiu, Ching-Hung,Wu, Chi-Han,Hsin, Ling-Wei,Tzen, Kai-Yuan,Cheng, Cheng-Yi,Ma, Kuo-Hsing,Shiue, Chyng-Yann
, (2019/08/01)
[18F]T807 is a potent tau protein imaging agent. In order to fulfill the demand from preclinical and clinical studies, we developed an automated one-pot two-step synthesis of this potent tau imaging agent and studied its stability, and dosimetr
Synthesis of dicationic carbazole and 4′-amino-(3,3'-bipyridine)-4-ol and the spectral characteristics of carbazoles
Wang,Li,Ye,Guo,Jia
, p. 4632 - 4636 (2013/07/25)
The dicationic carbazole compound, 3,6-dimethyl-3,6-diazacarbazole diiodide (8) was prepared with 3-bromopyridine as a starting material by a six-step synthesis. The intermediates and target compound were confirmed by IR, NMR and MS. Meanwhile, UV-visible and fluorescent characteristics of 3,6-diazacarbazole (7) and 3,6-dimethyl-3,6-diazacarbazole diiodide (8) were investigated. It was found that fluorescence decay over time of dicationic carbazole existed in low ionic strength and high ionic strength could stabilize the fluorescence of dicationic carbazole.
Pyridine analogues of nimesulide: Design, synthesis, and in vitro and in vivo pharmacological evaluation as promising cyclooxygenase 1 and 2 inhibitors
Renard, Jean-Fran?ois,Arslan, Deniz,Garbacki, Nancy,Pirotte, Bernard,De Leval, Xavier
supporting information; experimental part, p. 5864 - 5871 (2010/02/28)
Nonsteroidal anti-inflammatory drugs (NSAIDs) represent one of the most prescribed medications, although the chronic use of such pharmacological agents is commonly associated with numerous side effects. The demonstration that the use of COX-2 selective or