75007-92-0

Usage

Uses

Used in Pharmaceutical Industry:
3H-Imidazo[4,5-c]pyridine, 2-phenylis used as a key intermediate in the synthesis of various pharmaceutical compounds. Its unique structure and reactivity contribute to the development of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
3H-Imidazo[4,5-c]pyridine, 2-phenylis utilized as a building block in the creation of agrochemicals, such as pesticides and herbicides. Its diverse reactivity allows for the development of novel compounds with improved efficacy and selectivity in agricultural applications.
Used in Materials Science:
3H-Imidazo[4,5-c]pyridine, 2-phenylis employed in the development of advanced materials with unique properties. Its incorporation into materials can lead to the creation of new compounds with potential applications in various industries, such as electronics, coatings, and polymers.
Research and Development:
Due to the wide range of potential applications, ongoing research and development efforts are focused on exploring the uses of 3H-Imidazo[4,5-c]pyridine, 2-phenylin various fields. This includes the synthesis of new compounds, optimization of existing processes, and the discovery of novel applications for this versatile chemical compound.

InChI:InChI=1/C12H9N3/c1-2-4-9(5-3-1)12-14-10-6-7-13-8-11(10)15-12/h1-8H,(H,14,15)

Upstream product

• 54-96-6 3,4-diaminopyridine 
• 2876-13-3 N-benzylpyridinium chloride 
• 65-85-0 benzoic acid 
• 80862-35-7 1-Benzyl-3-amino-1,4-dihydro-4-pyridoneimine 
• 504-24-5 4-aminopyridine 
• 5221-44-3 N-(pyridin-4-yl)benzamide 
• 1678-49-5 3-Bromo-4-nitropyridine N-oxide 
• 100-51-6 benzyl alcohol 
• 13091-23-1 4-chloro-3-nitropyridine 
• 100-46-9 benzylamine 
• 100-52-7 benzaldehyde 
• 1094703-97-5 (E)-N⁽³⁾-benzylidenepyridine-3,4-diamine 
• 1681-37-4 4-amino-3-nitropyridine 
• 100-47-0 benzonitrile 

Downstream Products

• 1219458-23-7 3-benzyl-2-phenylimidazo[4,5-c]pyridine 
• 98383-05-2 C₂₆H₂₂N₈O₅S₂ 

Relevant academic research and scientific papers

Substituted 5-benzyl-2-phenyl-5H-imidazo[4,5-c]pyridines: A new class of pestivirus inhibitors

A novel class of inhibitors of pestiviruses (5-substituted 2-phenyl-5H-imidazo[4,5-c]pyridines) is described. Modification of the substituent in position 5 resulted in analogues with high activity (EC50 1000) aga

A one-step synthesis of substituted benzo- and pyridine-fused 1H-imidazoles

Substituted benzimidazoles and pyrimidazoles are an important group of heterocyclic aromatic organic compounds in the field of medicinal chemistry. A one-step microwave accelerated synthesis of substituted benzo- and pyridine-fused 1H-imidazoles has been described. Mechanistically, the reaction proceeds by reacting substituted 2-fluoronitrobenzene and substituted arylamine through the formation of N-hydroxy intermediate, which at higher temperature cleaves to afford the desired product. This approach achieved reductions in reaction times, higher yields, cleaner reactions than the previously described synthetic processes.

Oxidative Cyclization Approach to Benzimidazole Libraries

An efficient approach to the parallel synthesis of benzimidazoles from anilines is described. Library approaches to vary the N1 and C2 vectors of benzimidazoles are well established; however, C4-C7 variation has traditionally relied on 1,2-dianiline build

Photophysics of 2-(4′-amino-2′-hydroxyphenyl)-1H-imidazo-[4,5- c ]pyridine and its analogues: Intramolecular proton transfer versus intramolecular charge transfer

Photophysical characteristics of 2-(4′-amino-2′-hydroxyphenyl)-1H-imidazo-[4,5-c]pyridine (AHPIP-c) have been studied in various aprotic and protic solvents using UV-visible, steady state fluorescence and time-resolved fluorescence spectroscopic technique

Catalyst-free one-pot synthesis of benzimidazoles from 1,2-diaminoarenes and alcohols

A new and efficient protocol is described for the one-pot synthesis of benzimidazoles from a variety of aryl alcohols and 1,2-diaminoarenes. The yields were ranging from moderate to excellent. Moreover, the present method is utilizing alcohols instead of aldehydes and the reactions are carried out under solvent- and catalyst-free conditions, offering an environmentally benign process.

Selective autoxidation of benzylamines: Application to the synthesis of some nitrogen heterocycles

A green and remarkably simple synthesis of nitrogen heterocycles from benzylamines and anilines o-substituted by a cyclizable group has been developed based on selective uncatalyzed autoxidation of benzylamines.

Na2S2O4: A versatile reagent for the one-pot synthesis of 2-aryl-1h-imidazo[4,5-c]pyridines from 4-amino-3- nitropyridine and aldehydes via reductive cyclization

A highly efficient and versatile method for the synthesis of 2-aryl-1H-imidazo[4,5-c]pyridines 3 was achieved in one step via reductive cyclization of 4-amino-3-nitro-pyridines 4 with aromatic aldehydes in the presence of Na2S2O

New one-pot procedure for the synthesis of 2-substituted benzimidazoles

A highly selective synthesis of 2-substituted benzimidazole derivatives from the reaction of o-phenylendiamine derivatives and aromatic aldehydes in the presence of an organic salt, NH4OAc, in absolute ethanol is presented. The products were obtained by evaporating the solvent followed by a simple recrystallization with excellent yields. Copyright Taylor & Francis Group, LLC.

Synthesis of 3,4-diaminopyridine and imidazo[4,5-c]pyridines by nitration of 4-acylaminopyridines

New methods for the preparation of 3,4-diaminopyridine (5) and imidazo[4,5-c]pyridines 7a,7b based on direct nitration of 4- acylaminopyridines 3a, 3b have been explored.

2-phenylimidazio (4,5-c) pyridines

This invention provides for certain 2-phenylimidazo[4,5-c]pyridines, their pharmaceutical formulations, and their use as positive inotropic agents, bronchodilators, vasodilators, and anticoagulants.