167827-90-9

Basic information

• Product Name: 5,6-Dihydroxy-(4α,5α,6β,7β)-hexahydro-1,3-bis(4-(hydroxymethyl)phenylmethyl)-2-phenoxy-4,7-bis(phenyl-methyl)-1H-1,3,2-diazaphosphepine 2-oxide
• Synonyms: 5,6-Dihydroxy-(4α,5α,6β,7β)-hexahydro-1,3-bis(4-(hydroxymethyl)phenylmethyl)-2-phenoxy-4,7-bis(phenyl-methyl)-1H-1,3,2-diazaphosphepine 2-oxide
• CAS NO: 167827-90-9
• Molecular Weight: 678.765
• Mol File: 167827-90-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 5,6-Dihydroxy-(4α,5α,6β,7β)-hexahydro-1,3-bis(4-(hydroxymethyl)phenylmethyl)-2-phenoxy-4,7-bis(phenyl-methyl)-1H-1,3,2-diazaphosphepine 2-oxide(CAS DataBase Reference)
• NIST Chemistry Reference: 5,6-Dihydroxy-(4α,5α,6β,7β)-hexahydro-1,3-bis(4-(hydroxymethyl)phenylmethyl)-2-phenoxy-4,7-bis(phenyl-methyl)-1H-1,3,2-diazaphosphepine 2-oxide(167827-90-9)
• EPA Substance Registry System: 5,6-Dihydroxy-(4α,5α,6β,7β)-hexahydro-1,3-bis(4-(hydroxymethyl)phenylmethyl)-2-phenoxy-4,7-bis(phenyl-methyl)-1H-1,3,2-diazaphosphepine 2-oxide(167827-90-9)

Safety Data

• Hazardous Substances Data: 167827-90-9(Hazardous Substances Data)

Upstream product

• 180600-14-0 1,3-bis(4-(tetrahydropyranyloxymethyl)benzyl)-(4α,5α,6β,7β)-hexahydro-5,6-(1-methylidene)bis(oxy)-2-phenoxy-4,7-bisbenzyl-1H-1,3,2-diazaphosphepine-2-oxide 
• 177574-46-8 dibenzyl ((1R,1'R)-((4S,5S)-2,2-dimethyl-1,3-dioxolane-4,5-diyl)bis(2-phenylethane-1,1-diyl))dicarbamate 
• 153223-10-0 (2R,3S,4S,5R)-2,5-bis[N-(benzyloxycarbonyl)amino]-1,6-diphenyl-3,4-hexanediol 
• 770-12-7 O-phenyl phosphorodichloridate 

Downstream Products

• 180600-04-8 (3-endo,4-endo,6-exo)-2,7-bis(4-(hydroxymethyl)benzyl)-3,6-bisbenzyl-8-oxa-2,7-diaza-1-phosphabicyclo[3.2.1]octan-4-ol-1-oxide 

Relevant articles and documents

SUBSTITUTED BICYCLIC PHOSPHORAMIDES AND DERIVATIVES THEREOF

This invention relates to substituted bicyclic phosphoramides and derivatives thereof, useful as retroviral protease inhibitors and as standards and reagents in determining the ability of a potential pharmaceutical to inhibit viral replication or HIV protease, to pharmaceutical compositions comprising such compounds, and to methods of using these compounds for treating viral infection.