167887-37-8

Basic information

• Product Name: 3-AMINO-3-(4-BENZYLOXY-3-METHOXY-PHENYL)-PROPIONIC ACID
• Synonyms: RARECHEM AL BL 0062;3-AMINO-3-(4-BENZYLOXY-3-METHOXY-PHENYL)-PROPIONIC ACID;3-AMino-3-(4-(benzyloxy)-3-Methoxyphenyl)propanoic acid
• CAS NO: 167887-37-8
• Molecular Formula: C₁₇H₁₉NO₄
• Molecular Weight: 301.34
• Mol File: 167887-37-8.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-AMINO-3-(4-BENZYLOXY-3-METHOXY-PHENYL)-PROPIONIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 3-AMINO-3-(4-BENZYLOXY-3-METHOXY-PHENYL)-PROPIONIC ACID(167887-37-8)
• EPA Substance Registry System: 3-AMINO-3-(4-BENZYLOXY-3-METHOXY-PHENYL)-PROPIONIC ACID(167887-37-8)

Safety Data

• Hazardous Substances Data: 167887-37-8(Hazardous Substances Data)

Upstream product

• 2426-87-1 3-methoxy-4-(phenylmethoxy)benzaldehyde 
• 141-82-2 malonic acid 
• 100-39-0 benzyl bromide 
• 121-33-5 vanillin 

Downstream Products

• 72076-93-8 3-Amino-3-(4-hydroxy-3-methoxy-phenyl)-propionic acid 
• 167887-17-4 3-phthalimido-3-(4'-benzyloxy-3'-methoxyphenyl)propionic acid 

Relevant articles and documents

Novel benzylidenephenylpyrrolizinones with pleiotropic activities potentially useful in Alzheimer's disease treatment

This work describes the synthesis and the biological evaluation of novel benzylidenephenylpyrrolizinones as potential antioxidant, metal chelating or amyloid β (βA) aggregation inhibitors. Some derivatives exhibited interesting results in regard to several of the performed evaluations and appear as valuable Multi-Target Directed Ligands with potential therapeutic interest in Alzheimer's disease. Among them, compound 29 particularly appears as a valuable radical and NO scavenger, a Cu(II) and Fe(II) chelating agent and exhibits moderate βA aggregation inhibition properties. These activities, associated to a good predictive bioavailability and a lack of cytotoxicity, design it as a promising hit for further in vivo investigation.

Coloured artefacts formed by oxidation of benzene-1,2,4-triol and β-dopa during the extraction of cortinarius violaceus (agaricales) with alcohols

An array of coloured artefacts was formed upon extraction of the mushroom Cortinarius violaceus with methanol. The structures of these pigments were determined by spectroscopic investigations, including NMR and mass spectrometric analyses. Cortiviolate A and dihydrocortiviol A arise by oxidative dimerization of benzene-1,2,4-triol, and cortiviolate B is formed by an unprecedented oxidative rearrangement of β-dopa. The oxidations are caused by iron(III) ions, released from the iron complex of (R)-β-dopa- the native violet pigment of the mushroom. In the course of these investigations, syntheses of the cortiviolates, dihydrocortiviol A, gomphilactone, and two related dilactones were carried out. Copyright