167892-85-5Relevant academic research and scientific papers
A chemoenzymatic synthesis of A-ring key-intermediates for 1 α,25-dihydroxyvitamin D3 and analogues
Vrielynck, Sara,Vandewalle, Maurits,Garcia, Ana M.,Mascarenas, Jose L.,Mourino, Antonio
, p. 9023 - 9026 (2007/10/02)
A short and practical synthesis of the 1,7-enyne A-ring intermediate and of Uskokovic's phosphine-oxide precursor is described starting from the aldol product of acrolein with t-butyl acetate. Enantiopure βhydroxy ester is obtained upon lipase-catalyzed resolution.
