167904-18-9

Basic information

• Product Name: [2R-(2α,3α,4α,5β)]-3,4,5-tris(phenylmethoxy)-2-[(phenylmethoxy)methyl]piperidine
• Synonyms: [2R-(2α,3α,4α,5β)]-3,4,5-tris(phenylmethoxy)-2-[(phenylmethoxy)methyl]piperidine
• CAS NO: 167904-18-9
• Molecular Weight: 523.672
• Mol File: 167904-18-9.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: [2R-(2α,3α,4α,5β)]-3,4,5-tris(phenylmethoxy)-2-[(phenylmethoxy)methyl]piperidine(CAS DataBase Reference)
• NIST Chemistry Reference: [2R-(2α,3α,4α,5β)]-3,4,5-tris(phenylmethoxy)-2-[(phenylmethoxy)methyl]piperidine(167904-18-9)
• EPA Substance Registry System: [2R-(2α,3α,4α,5β)]-3,4,5-tris(phenylmethoxy)-2-[(phenylmethoxy)methyl]piperidine(167904-18-9)

Safety Data

• Hazardous Substances Data: 167904-18-9(Hazardous Substances Data)

Upstream product

• 158349-25-8 (3R,4S,5S,6R)-3,4,5-tris(benzyloxy)-6-((benzyloxy)methyl)piperidin-2-one 
• 930113-63-6 2,3,4,6-tetra-O-benzyl-D-arabinohexos-5-ulose 
• 167904-14-5 2,3-di-O-benzyl-4,6-O-benzylidene-5-O-(tol-4-ylsulfonyl)-L-altrononitrile 
• 167904-05-4 2,3,4,6-tetra-O-benzyl-L-altrononitrile 
• 167904-03-2 2,3,4,6-tetra-O-benzyl-D-galactononitrile 
• 167904-10-1 2,3-di-O-benzyl-4,6-O-benzylidene-D-galactononitrile 
• 168037-62-5 (Z)-2,3,4,6-tetra-O-benzyl-D-galactose oxime 
• 168037-64-7 2,3-Bis-O-(phenylmethyl)-4,6-O-(phenylmethylene)-D-galactopyranose 
• 100-39-0 benzyl bromide 
• 300547-63-1 [1S-(1α,2β,3α,4β,5β)]-2-(methoxyamino)-3,4,5-tris(phenylmethoxy)-1-[(phenylmethoxy)methyl]cyclopentanol 
• 168037-63-6 (5R,6S,7S,8S)-6,7,8-tris(benzyloxy)-5-<(benzyloxy)methyl>-5,6,7,8-tetrahydro-tetrazolo<1,5-a>pyridine 
• 167904-06-5 2,3,4,6-tetra-O-benzyl-5-O-(tol-4-ylsulfonyl)-L-altrononitrile 
• 167904-11-2 2,3-di-O-benzyl-4,6-O-benzylidene-L-arabino-hex-5-ulosononitrile 

Downstream Products

• 1448811-38-8 N-(4'-azidobutyl)-2,3,4,6-tetra-O-benzyl-1-deoxygalactonojirimycin 

Relevant articles and documents

SYNTHESIS OF AN AZASUGAR AND INTERMEDIATES THEREOF

The present invention relates to a process for the preparation of migalastat of formula (I) and intermediates useful in the synthesis thereof. The process comprises the double reductive amination reaction of a compound of formula (VI).

Radical cyclization in heterocycle synthesis. Part 9: A novel synthesis of aminocyclitols and related compounds via stannyl radical cyclization of oxime ethers derived from sugars

Stannyl radical addition-cyclization of oxime ethers derived from D-glucose, D-galactose, and D-xylose proceeded smoothly to afford alkoxyamino alcohols which were effectively converted into two types of glycosidase inhibitors or its candidates such as aminocyclitols, 1-deoxynojirimycin, and 1-deoxygalactostatin via reductive ring-expansion of trans alkoxyamino alcohols. (C) 2000 Elsevier Science Ltd.