16795-37-2

Usage

Uses

Used in Fluorescent Dye Applications:
DMBA is utilized as a fluorescent dye in various fields, including biotechnology and medical research, due to its strong absorption in the ultraviolet and visible range. It aids in fluorescent labeling and imaging processes, enhancing the visualization and analysis of biological samples.
Used in Organic Synthesis:
As a reagent in organic synthesis, DMBA is employed in the production of numerous organic compounds. Its distinctive chemical structure and reactivity make it a valuable asset in the synthesis of a diverse array of molecules, contributing to advancements in the chemical and pharmaceutical industries.
Used in Research and Development:
DMBA's properties also make it a useful tool in research and development, particularly in the study of molecular interactions and the development of new materials and compounds with potential applications in various industries.
Used in Analytical Chemistry:
In analytical chemistry, DMBA can be employed as a reference compound or standard for the calibration of instruments and methods that measure the absorption of light in the ultraviolet and visible range, ensuring accurate and reliable results in various analytical techniques.
Used in Pharmaceutical Industry:
Although not explicitly mentioned in the provided materials, DMBA's potential applications in the pharmaceutical industry could include its use in the development of new drugs or drug candidates, given its unique chemical properties and reactivity. Further research and development would be necessary to explore these possibilities fully.

Upstream product

• 350-03-8 methyl-3-pyridylketone 
• 100-10-7 4-dimethylamino-benzaldehyde 

Downstream Products

• 1347755-34-3 N,N-dimethyl-4[1-phenyl-3-(pyridin-3-yl)-4,5-dihydro-1Hpyrazol-5-yl]benzenamine 
• 1347755-29-6 N,N-dimethyl-4[3-(pyridin-3-yl)-4,5-dihydro-1H-pyrazol-5-yl]benzenamine 
• 1418140-24-5 2-amino-4-(3'-pyridyl)-6-(4''-dimethylaminophenyl)pyrimidine 

Relevant academic research and scientific papers

A regioselective and convenient one-pot multicomponent synthesis of 9-amino-3,5-diaryl-4,9-dihydro-5H-[1,2,4]triazolo[5,1-c][1,2,4]triazepine-8-thiol

An efficient and environment-friendly procedure for the synthesis of a new series of nitrogen bridge-head [1,2,4]triazolo[5,1-c][1,2,4]triazepine derivatives through one-pot three-component reaction of polyfunctional triazole with aromatic aldehydes and acetophenone derivatives using alcoholic sodium hydroxide solution. The same new products were prepared in classical route through reaction of triazole with the corresponding chalcones under the same conditions.

Experimental and Theoretical Studies of the Spectroscopic Properties of Chalcone Derivatives

Newly synthesized, differently substituted chalcones (1,3-diaryl-2-propen-1-ones) have been studied using steady-state and time-resolved techniques combined with quantum-chemical modelling. To explore spectroscopic structure - property relationships the substituent (acceptor moiety) was chosen according to systematic variation in the Hammett parameter. It was shown that photophysical properties of the studied donor-acceptor (D-A) molecules can be predicted in terms of a simple model from the properties of individual chromophores (composite-model of decoupled moieties: donor (D) and acceptor (A)). The results of spectroscopic measurements also indicate that for investigated D-A fluorophores in medium-polar solvent, the initially populated, locally excited (LE) state (where the fundamental role plays donor moiety (D*-A)) reacts further to produce intramolecular charge transfer (ICT) state. Additionally, the experimental absorption (Mge) and fluorescence (Meg) transition dipole moments were calculated on the basis of spectroscopic data and compared with results of our quantum-chemical calculations. The absorption transition dipole moment was found to vary linearly with the Hammett substituent coefficient (σ).

Preparation and biological evaluation of novel pyrimidines from novel chalcones

Pyrimidines are the parent substances of a large group of heterocyclic compounds and play a vital role in many biological processes, as found in nucleic acids, several vitamins, coenzymes, purines and possess therapeutic activities like antimicrobial, anti-inflammatory, anticancer, antiviral, antitubercular and antimalarial activities. In the present study an attempt is made to synthesize pyrimidines from novel chalcones which provide an easy route of synthesis and chalcones themselves possess antimicrobial activity. All these compounds were characterized by means of their IR, 1H NMR, 13C NMR, and mass spectral data. These compounds were evaluated for antimicrobial activity by cup plate method.