16807-21-9

Upstream product

• 493-57-2 benzo-[b]thiophene-2,3-dione 
• 215245-36-6 Chloro-oxo-thioacetic acid S-phenyl ester 
• 108-98-5 thiophenol 

Downstream Products

• 198481-48-0 [2-Benzo[d]isothiazol-3-yl-4-(4-methoxy-phenyl)-thiazol-5-yl]-acetic acid ethyl ester 
• 198481-49-1 [2-Benzo[d]isothiazol-3-yl-4-(4-chloro-phenyl)-thiazol-5-yl]-acetic acid ethyl ester 
• 198481-47-9 (2-Benzo[d]isothiazol-3-yl-4-phenyl-thiazol-5-yl)-acetic acid ethyl ester 
• 40991-34-2 1,2-benzisothiazole-3-carboxylic acid 
• 40991-36-4 benzo[d]isothiazole-3-carboxylic acid ethyl ester 

Relevant academic research and scientific papers

CASPASE INHIBITOR AND PHARMACEUTICAL COMPOSITION, USE AND THERAPEUTIC METHOD THEREOF

Disclosed are a class of compounds as a caspase inhibitor, and in particular the compound as shown in formula (I) or a pharmaceutically acceptable salt thereof, and the use of the compound in treating caspase-related diseases.

2-AZA-BICYCLO[3.1.0]HEXANE DERIVATIVES

The invention relates to novel 2-aza-bicyclo[3.1.0]hexane derivatives of Formula (I) wherein A, B, n and R1 are as described in the description, and to the use of such compounds, or of pharmaceutically acceptable salts of such compounds, as medicaments, especially as orexin receptor antagonists.

DIHYDROIMIDAZOTHIAZOLE DERIVATIVES

Compounds of formula (I): or pharmaceutically acceptable salts thereof, exhibit 5-HT1A agonism in addition to noradrenaline reuptake inhibition and optionally also 5-HT reuptake inhibition are useful for the treatment of obesity.

PROCESS FOR THE PREPARATION OF 6-(PERFLUOROALKYL)URACIL COMPOUNDS FROM CARBAMATE COMPOUNDS

An improved process for the preparation of 6-(perfluoroalkyl)uracil compounds having structural formula (I) from carbamate compounds having structural formula (II).

Processes and intermediate compounds for the preparation of 2-(N,N-disubstituted) amino-4-(perfluoroalkyl)-1, 3- oxazin-6-one and 6-(perfluoroalkyl) uracil compounds

An improved process and intermediate compounds for the preparation of 2-(N,N-disubstituted)amino-4-(perfluoroalkyl)-1,3-oxazin-6-one compounds having the structural formula I and an improved process for the preparation of 6-(perfluoroalkyl)uracil compound

Herbicidal 3 -heterocyclic substituted benzisothiazole and benzisoxazole compounds

There are provided 3-heterocyclic substituted benzisothiazole and benzisoxazole compounds having the structural formula I where Q, X, X1 and Z are defined as in claim 1. Further provided are compositions and methods comprising those compounds for the control of undesirable plant species.

Process for the preparation of 6-(perfluoroalkyl) uracil compounds form urea compounds

An improved process for the preparation of 6-(perfluoroalkyl)uracil compounds having the structural formula I from urea compounds having the structural formula II

Process for the preparation of 6-(perfluoroalkyl) uracil compounds from 2-(N,N-disubstituted) amino-4-(perfluoroalkyl)-1,3-oxazin-6-one compounds

An improved process for the preparation of 6-(perfluoroalkyl)uracil compounds having the structural formula I from 2-(N,N-disubstituted)amino-4-(perfluoroalkyl)-1,3-oxazin-6-one compounds having the structural formula II

3-(1,2-benzisothiazol- and isoxazol-5-Y1)-2,4(1H,3H)-pyrimidinedione or thione and 3-(1,2-benzisothiazol- and isoxazol-5-y1)-4(3H)-pyrimidinone or thione herbicidal agents

There are provided 3-(1,2-benzisothiazol- and isoxazol-5-yl)-2,4(1H,3H)-pyrimidinedione or thione compounds of formula I and 3-(1,2-benzisothiazol- and isoxazol-5-yl)-4(3H)-pyrimidinone or thione compounds of formula II Further provided are compositions and methods comprising those compounds for the control of undesirable plant species.

Benzisoxazole- and Benzisothiazole-3-carboxamides as Potential Atypical Antipsychotic Agents

A series of benzisoxazole- and benzisothiazole-3-carboxamides has been prepared and tested for potential antipsychotic activity.In general, the compounds showed an affinity for dopamine D2 and serotonin 5HT2A and 5HT1A rec