168126-00-9Relevant articles and documents
One-pot synthetic routes to multiply substituted indene derivatives by hydrolysis of zirconocene-mediated intermolecular coupling reactions of aromatic ketones and alkynes
Xi, Zhenfeng,Guo, Ruiyun,Mito, Shizue,Yan, Hongliang,Kanno, Ken-ichiro,Nakajima, Kiyohiko,Takahashi, Tamotsu
, p. 1252 - 1257 (2003)
Two one-pot multicomponent synthetic methods for highly substituted indenes are described. The intermolecular coupling of aromatic ketones with alkynes on low-valent zirconocene species generates oxazirconacyclopentenes, which upon hydrolysis with 20% HCl
Synthesis of 1,1,4,4-tetrabromo-2-butenes and related compounds via desilylation-bromination of silylated 1,3-butadiene derivatives
Xi, Zhenfeng,Liu, Xiaozhong,Lu, Jianming,Bao, Fengyu,Fan, Hongtao,Li, Zhiping,Takahashi, Tamotsu
, p. 8547 - 8549 (2007/10/03)
The combination of zirconocene-mediated coupling of silylated alkynes with a protonation-desilylation or bromination-desilylation process afforded otherwise unavailable butadiene derivatives. When (E,E)-2,3-dialkyl-1,4- bis(trimethylsilyl)-1,3-butadienes were treated with 3 equiv of Br2 in CH2Cl2, (E)-2,3-dialkyl-1,1,4,4-tetrabromo-2-butenes were obtained in excellent yields with perfect stereoselectivity.
