168126-96-3

Basic information

• Product Name: 2-Amino-6-(4-chloro-phenyl)-4-trifluoromethyl-nicotinamide
• Synonyms: 2-Amino-6-(4-chloro-phenyl)-4-trifluoromethyl-nicotinamide
• CAS NO: 168126-96-3
• Molecular Weight: 315.682
• Mol File: 168126-96-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-Amino-6-(4-chloro-phenyl)-4-trifluoromethyl-nicotinamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Amino-6-(4-chloro-phenyl)-4-trifluoromethyl-nicotinamide(168126-96-3)
• EPA Substance Registry System: 2-Amino-6-(4-chloro-phenyl)-4-trifluoromethyl-nicotinamide(168126-96-3)

Safety Data

• Hazardous Substances Data: 168126-96-3(Hazardous Substances Data)

Upstream product

• 155635-63-5 2-amino-3-cyano-4-trifluoromethyl-6-p-chlorophenylpyridine 
• 147381-62-2 6-(4-chlorophenyl)-3-cyano-4-trifluoromethyl-2(1H)-pyridone 

Relevant articles and documents

A simple one pot synthesis of novel tricyclic quinazolinones

Synthesis of a series of tricyclic quinazolinones have been accomplished starting from anthranilamide and 1,3-cyclic dione promoted by TsOH·H2O The protocol presented herein based on retro-Dieckmann type reaction, leading to incorporation of dione as an acyclic unit into the product. Simple reaction conditions, broad scope, excellent yields are the advantages of this protocol. Further, this methodology is extended to the synthesis of pyridopyrimidinones and benzimidazopyridines.