168210-66-0Relevant academic research and scientific papers
INHIBITORS OF FACTOR XA AND OTHER SERINE PROTEASES INVOLVED IN THE COAGULATION CASCADE
-
Page 86, (2010/02/06)
This invention discloses amino acid derivatives which display inhibitory effects on the serine protease factor Xa. The invention also discloses pharmaceutically acceptable salts of the compounds, pharmaceutically acceptable compositions comprising the compounds or their salts, methods for the preparation of the compounds, and methods of using them as therapeutic agents for treating or preventing disease states in mammals characterized by abnormal thrombosis.
Synthesis of methyl 3-amino-3-pyrrolidinecarboxylates: A convenient access to cucurbitine and analogues
Mamoun,Benhaoua,Danion-Bougot,Danion
, p. 1295 - 1302 (2007/10/02)
Cycloaddition of N-benzylazomethine ylide 7 to methyl 2-(diphenylmethyleneamino) or 2-(benzylideneamino) acrylates affords the tittle compounds after deprotection by catalytic hydrogenation.
