93102-06-8Relevant articles and documents
Farnesyl transferase inhibitors, their preparation, the pharmaceutical compositions which contain them and their use in the preparation of medicaments
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, (2008/06/13)
Novel products of formula (I), their preparation, the pharmaceutical compositions which contain them and their use in the preparation of medicaments. In the formula (I), the following substituents are among the preferred: Ar represents a substituted or co
N-(TRIMETHYLSILYLMETHYL)AMINOMETHYL ETHERS AS AZOMETHINE YLIDE SYNTHONS. A NEW AND CONVENIENT ACCESS TO PYRROLIDINE DERIVATIVES
Hosomi, Akira,Sakata, Yasuyuki,Sakurai, Hideki
, p. 1117 - 1120 (2007/10/02)
The title compounds, readily prepared from (trimethylsilylmethyl)amines, formaldehyde and an alcohol, react with electron deficient alkenes in the presence of iodosilane or silyl triflate in combination with cesium fluoride to give the corresponding pyrrolidine derivatives stereospecifically in excellent yield.