168329-41-7Relevant academic research and scientific papers
Genosnip: SNP genotyping by MALDI-TOF MS using photocleavable oligonucleotides
Wenzel,Elssner,Fahr,Bimmler,Richter,Thomas,Kostrzewa
, p. 1579 - 1581 (2003)
A photocleavable o-nitrobenzyl CE phosphoramidite building-block was synthesised and incorporated within oligonucleotides. After allele-specific primer extension, desalting was performed using genostrep purification plates. Release of the SNP information
Photocleavable morpholino oligos with integral photolinkers for modulating the activity of any selected gene transcript by exposure to light
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Paragraph 0075; 0076, (2013/03/26)
Morpholinos are widely used to block the activity of selected single-stranded genetic sequences. This invention comprises Morpholinos containing one or more integral photolinkers (Photo-Morpholinos) wherein the photolinkers are directly incorporated into
Tandem catalysis by lipase in a vinyl acetate-mediated cross-aldol reaction
Kumar, Manjeet,Shah, Bhahwal A.,Taneja, Subhash C.
experimental part, p. 1207 - 1212 (2011/06/25)
The lipase Novozym435 (0.6% w/w) was used in tandem with organocatalysts in a first vinyl/isopropenyl acetate-mediated aldol reaction. The reaction was facilitated through the lipase-catalyzed in situ generation of acetaldehyde/acetone. The important features of the present methodology include the mild and facile reaction conditions, regenerability of the lipase, comparatively high yields and minimal side product formation.
