168399-37-9Relevant academic research and scientific papers
Asymmetric Synthesis of (3R,5R)- and (3S,5S)-2,6-Dimethylheptane-3,5-diol, useful C2 Chiral Auxiliaries
Jacoby, C.,Braekman, J.C.,Daloze, D.
, p. 753 - 756 (2007/10/02)
(R,R)- and (S,S)-2,6-Dimethylheptane-3,5-diol, which are useful C2 chiral auxiliaries, have been both synthesized in high optical purity from 2,6-dimethylheptane-3,5-dione, by using as key step a Sharpless kinetic resolution.
Chiral Organometallic Reagents, IV Stereoselective Formation of β-Silyloxy-α-bromoalkyllithium Compounds
Hoffmann, Reinhard W.,Julius, Manfred
, p. 811 - 822 (2007/10/02)
The diastereomeric carbenoids 4 have been generated by diastereoselective (84:16) exchange of the diastereotopic bromine atoms in the dibromo compound 3 for lithium at -120 deg C.The implication of the observed diastereoselectivity for the Nozaki ring-expansion method is discussedKey words: Carbenoids / Halogen-metal exchange / Diastereotopic groups
