168418-08-4

Basic information

• Product Name: 1α,25-dihydroxyvitamin D3-1-deoxy-1α-t-butyldimethylsilyloxy-3β-3-(4-azido-2-nitrophenyl)aminopropyl ether
• CAS NO: 168418-08-4
• Molecular Weight: 750.11
• Mol File: 168418-08-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1α,25-dihydroxyvitamin D3-1-deoxy-1α-t-butyldimethylsilyloxy-3β-3-(4-azido-2-nitrophenyl)aminopropyl ether(CAS DataBase Reference)
• NIST Chemistry Reference: 1α,25-dihydroxyvitamin D3-1-deoxy-1α-t-butyldimethylsilyloxy-3β-3-(4-azido-2-nitrophenyl)aminopropyl ether(168418-08-4)
• EPA Substance Registry System: 1α,25-dihydroxyvitamin D3-1-deoxy-1α-t-butyldimethylsilyloxy-3β-3-(4-azido-2-nitrophenyl)aminopropyl ether(168418-08-4)

Safety Data

• Hazardous Substances Data: 168418-08-4(Hazardous Substances Data)

Upstream product

• 168418-07-3 1α,25-dihydroxyvitamin D3-1-deoxy-1α-t-butyldimethylsilyloxy-3β-2-cyanoethyl ether 
• 98728-26-8 1α-tert-butyldimethylsilylether of 1α-25-dihydroxyvitamin D₃ 

Relevant articles and documents

Aminopropylation of vitamin D hormone (1α,25-dihydroxyvitamin D3), its biological precursors, and other steroidal alcohols: An anchoring moiety for affinity studies of sterols

In this communication we describe a simple two-step procedure for the conversion of several steroidal alcohols to their aminopropyl ether derivatives.To demonstrate the usefulness of this procedure we synthesized a second-generation photoaffinity labeling analog of 1α,25-dihydroxyvitamin D3, and a 25-hydroxyvitamin D3 derivative containing a long and chemically stable tether.Utilities of these aminopropyl ether derivatives of steroids in various affinity studies of receptor proteins are discussed. (Steroids 60:530-533, 1995)