168424-13-3Relevant academic research and scientific papers
Synthesis of the first 1,2,4-triazine C-nucleoside and its transformation to novel pyridine C-nucleosides by 'inverse' [4 + 2]-cycloaddition reactions
Richter,Seitz
, p. 175 - 180 (1995)
The anomeric C-glycosyl precursors 6 and 7, appropriate for C-nucleoside synthesis and functionalized by an imidate group, were prepared. They were utilized as heterodienophiles in a Diels-Alder reaction with inverse electron demand to yield the O-benzyl
A new C-nucleoside analogue of tiazofurin: Synthesis and biological evaluation of 2-β-D-ribofuranosylimidazole-4-carboxamide (imidazofurin)
Franchetti, Palmarisa,Marchetti, Stefano,Cappellacci, Loredana,Yalowitz, Joel A.,Jayaram, Hiremagalur N.,Goldstein, Barry M.,Grifantini, Mario
, p. 67 - 69 (2001)
2-β-D-Ribofuranosylimidazole-4-carboxamide, an imidazole analogue of the antitumor agent tiazofurin, was synthesized and evaluated for the growth inhibitory activity of human myelogenous leukemia K562 cells. (C) 2000 Elsevier Science Ltd.
