16844-42-1

Usage

InChI:InChI=1/C9H8N2O2/c12-9-7-11(10-13-9)6-8-4-2-1-3-5-8/h1-5,7H,6H2/p+1

Upstream product

• 17572-00-8 3-Benzyl-N-nitroso-5-sydnone imine 
• 94237-59-9 2-phenyl-2,2'-nitrosoazanediyl-bis-acetic acid 
• 7689-50-1 N-benzyl glycine hydrochloride 
• 100-46-9 benzylamine 
• 17136-36-6 N-benzylglycine 
• 6436-90-4 ethyl 2-(benzylamino)acetate 
• 27023-48-9 3-(carboxy-phenyl-methyl)-sydnone 

Downstream Products

• 33549-55-2 3-(1,2-diphenyl-ethyl)-sydnone 
• 29179-69-9 3-benzyl-4-methylsulfanyl-sydnone 
• 31180-69-5 3-benzyl-4-formyl-sydnone 
• 105994-62-5 (1-benzyl-3-phenyl-1H-pyrazol-4-yl)phenylmethanone 
• 105994-61-4 3-benzoyl-4-phenyl-1-benzylpyrazole 
• 28667-51-8 10-benzyl-9,10-diazatetracyclo<6.3.0.0.^4,110.^5,9>undecane 
• 1160614-57-2 1-benzyl-3-phenyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole 
• 4918-34-7 3-benzyl-4-carboxy-sydnone 

Relevant academic research and scientific papers

Sydnone Cycloaddition Route to Pyrazole-Based Analogs of Combretastatin A4

The combretastatins are an important class of tubulin-binding agents. Of this family, a number of compounds are potent tumor vascular disrupting agents (VDAs) and have shown promise in the clinic for cancer therapy. We have developed a modular synthetic r

SUBSTITUTED CYCLOALKYLS AS MODULATORS OF THE INTEGRATED STRESS PATHWAY

Provided herein are compounds, compositions, and methods useful for modulating the integrated stress response (ISR) and for treating related diseases, disorders and conditions.

Synthesis of 2 H-indazoles by the [3 + 2] dipolar cycloaddition of sydnones with arynes

A rapid and efficient synthesis of 2H-indazoles has been developed using a [3 + 2] dipolar cycloaddition of sydnones and arynes. A series of 2H-indazoles have been prepared in good to excellent yields using this protocol, and subsequent Pd-catalyzed coupl

Synthesis and reactions of 9,10-diazatetracyclo-[6.3.0.0.4,110.5.9]undecanes

The tandem 1,3-dipolar cycloaddition between sydnones and 1,5-cyclooctadiene provides 9,10-diazatetracyclo[6.3.0.0.4,110.5,9]undecanes (the Weintraub reaction) in modest to good yields.

Reaction of Sydnones with Oxygen

The reaction of 3-benzyl- and 3-(p-chlorobenzyl)-4-phenylsydnones (1a and 1b) and of 3-benzylsydnone (1c) with oxygen at room temperature in the dark is described.Possible rationalizations for the formation of the products obtained are suggested.