168476-34-4Relevant academic research and scientific papers
Studies on the Synthesis of Some Styryl-3-cyano-2(1H)-pyridinethiones and Polyfunctionally Substituted 3-Aminothienopyridine Derivatives
Ho, Yuh Wen,Wang, Ing Jing
, p. 819 - 826 (2007/10/02)
The 3-cyano-4,6-dimethyl-2(1H)-pyridinethione was condensed with benzaldehyde in basic solution leads to styryl-3-cyano-2(1H)-pyridinethiones.Treatment of cinnamicaldehyde with cyanothioacetamide to give cinnamylidencyanothioacetamide, which can be cyclized with the appropriate ketones to afford the 3-cyano-5,6-polymethylene-4-styryl-2(1H)-pyridinethione derivatives.The polyfunctionally substituted 3-aminothienopyridine derivatives were obtained in good yield by cyclization of 3-cyano-2(1H)-pyridinethione derivatives with appropriate α-halogeno carbonyl compounds and nitrile, respectively.
