1685-18-3

Basic information

• Product Name: 1-Pentanone, 1-(2-amino-5-chlorophenyl)-
• CAS NO: 1685-18-3
• Molecular Formula: C11H14ClNO
• Molecular Weight: 211.691
• Mol File: 1685-18-3.mol

Chemical Properties

• CAS DataBase Reference: 1-Pentanone, 1-(2-amino-5-chlorophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Pentanone, 1-(2-amino-5-chlorophenyl)-(1685-18-3)
• EPA Substance Registry System: 1-Pentanone, 1-(2-amino-5-chlorophenyl)-(1685-18-3)

Safety Data

• Hazardous Substances Data: 1685-18-3(Hazardous Substances Data)

Usage

Functional groups

Ketone, amino, phenyl ring, chloro substitution

Usage

Intermediate for the synthesis of various drugs and organic compounds in the pharmaceutical and chemical industries, research and development for potential applications in medical and industrial processes, production of agrochemicals and specialty chemicals.

Upstream product

• 5922-60-1 2-amino-5-chlorobenzonitrile 

Relevant articles and documents

Catalyst-free geminal aminofluorination of ortho-sulfonamide-tethered alkylidenecyclopropanes via a Wagner-Meerwein rearrangement

A catalyst-free intramolecular geminal aminofluorination of ortho-sulfonamide-tethered alkylidenecyclopropanes has been developed. The reaction proceeded through two SET processes with Selectfluor to give a fluorinated cyclopropylcarbinyl cation and a further Wagner-Meerwein rearrangement to generate a cyclobutyl carbocation, which undergoes intramolecular nucleophilic capture by amide to forge fluorinated cyclobuta[b]indoline derivatives. A polycyclic multi-fluorinated byproduct was also formed through a Ritter-type reaction in some cases.