1685-23-0Relevant academic research and scientific papers
Discovery of novel benzoxazinones as potent and orally active long chain fatty acid elongase 6 inhibitors
Mizutani, Takashi,Ishikawa, Shiho,Nagase, Tsuyoshi,Takahashi, Hidekazu,Fujimura, Takashi,Sasaki, Takahide,Nagumo, Akira,Shimamura, Ken,Miyamoto, Yasuhisa,Kitazawa, Hidefumi,Kanesaka, Maki,Yoshimoto, Ryo,Aragane, Katsumi,Tokita, Shigeru,Sato, Nagaaki
supporting information; experimental part, p. 7289 - 7300 (2010/06/16)
A series of benzoxazinones was synthesized and evaluated as novel long chain fatty acid elongase 6 (ELOVL6) inhibitors. Exploration of the SAR of the UHTS lead 1a led to the identification of (S)-1y that possesses a unique chiral quarternary center and a
Control of parasites in animals by the use of novel trifluoromethanesulfonanilide oxime ether derivatives
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Page/Page column 36; 9/12, (2010/10/20)
Novel trifluoromethanesulfonanilide oxime ether compounds useful for controlling endo and/or ectoparasites in the environment are provided, together with methods of making the same, and methods of using the inventive compounds to treat parasite infestations in vivo or ex vivo.
