168569-15-1Relevant academic research and scientific papers
Isolation and structure determination of Cryptophycins 38, 326, and 327 from the terrestrial Cyanobacterium Nostoc sp. GSV 224
Chaganty, Sreedhara,Golakoti, Trimurtulu,Heltzel, Carl,Moore, Richard E.,Yoshida, Wesley Y.
, p. 1403 - 1406 (2004)
Cryptophycin-38 (2), -326 (3), and -327 (4) are three new trace constituents of the terrestrial cyanobacterium Nostoc sp. GSV 224. Cryptophycin-38 is a stereoisomer of cryptophycin-1 (1) and to date is the only naturally occurring analogue that possesses
Frontiers and opportunities in chemoenzymatic synthesis
Mortison, Jonathan D.,Sherman, David H.
scheme or table, p. 7041 - 7051 (2010/12/20)
Natural product biosynthetic pathways have evolved enzymes with myriad activities that represent an expansive array of chemical transformations for constructing secondary metabolites. Recently, harnessing the biosynthetic potential of these enzymes through chemoenzymatic synthesis has provided a powerful tool that often rivals the most sophisticated methodologies in modern synthetic chemistry and provides new opportunities for accessing chemical diversity. Herein, we describe our research efforts with enzymes from a broad collection of biosynthetic systems, highlighting recent progress in this exciting field.
