16865-25-1 Usage
Uses
Used in Electronics Industry:
2,4,5,6,7-PENTABROMO-1H-BENZOIMIDAZOLE is used as a flame retardant additive in the electronics industry to enhance the fire safety of electronic devices and components. Its application helps to slow down the combustion process and reduce the risk of fire-related accidents.
Used in Textile Industry:
In the textile industry, 2,4,5,6,7-PENTABROMO-1H-BENZOIMIDAZOLE is used as a flame retardant in fabrics and materials to improve their resistance to fire. This is particularly important for products that come into contact with high temperatures or are used in environments with increased fire risk.
Used in Building Materials:
2,4,5,6,7-PENTABROMO-1H-BENZOIMIDAZOLE is utilized as a flame retardant in building materials to reduce the flammability of construction products such as insulation, wall coverings, and upholstery. This helps to improve the overall fire safety of buildings and protect occupants in the event of a fire.
However, due to the growing awareness of the potential health and environmental impacts of 2,4,5,6,7-PENTABROMO-1H-BENZOIMIDAZOLE, there is a shift towards finding safer alternatives for flame retardancy in various applications.
Check Digit Verification of cas no
The CAS Registry Mumber 16865-25-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,6,8,6 and 5 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 16865-25:
(7*1)+(6*6)+(5*8)+(4*6)+(3*5)+(2*2)+(1*5)=131
131 % 10 = 1
So 16865-25-1 is a valid CAS Registry Number.
InChI:InChI=1/C7HBr5N2/c8-1-2(9)4(11)6-5(3(1)10)13-7(12)14-6/h(H,13,14)
16865-25-1Relevant academic research and scientific papers
From a MMP2/CK2 multitarget approach to the identification of potent and selective MMP13 inhibitors
Pastor, Miryam,Zapico, José María,Coderch, Claire,Maslyk, Maciej,Panchuk, Rostyslav,De Pascual-Teresa, Beatriz,Ramos, Ana
, p. 916 - 929 (2019/01/30)
In this article, we describe our efforts in the search of MMP2/CK2 dual targeting inhibitors. We have followed a rational drug design approach based on our experience in the selective inhibition of these two enzymes. We have successfully obtained highly a
Polyhalogenobenzimidazoles: Synthesis and their inhibitory activity against casein kinases
Andrzejewska, Mariola,Pagano, Mario A.,Meggio, Flavio,Brunati, Anna Maria,Kazimierczuk, Zygmunt
, p. 3997 - 4002 (2007/10/03)
A series of novel polyhalogenated benzimidazoles have been prepared by exhaustive bromination of a variety of 2-substituted benzimidazoles. The efficacy of both new compounds and a number of their previously described cognates as inhibitors of casein kinases CK1, CK2 and G-CK was investigated. The type of N-1 alkyl substituent as well as introduction of a polyfluoroalkyl moiety at position 2 did not markedly influence the inhibitory efficacy toward CK2 of the respective 4,5,6,7-tetrabromobenzimidazole derivatives which conversely were almost ineffective toward CK1 and G-CK. However, 4,5,6,7-tetrabromobenzimidazoles substituted at position 2 with either chlorine, bromine or sulfur atom, while manifesting a still considerable inhibitory activity against CK2 (IC50 in the 0.49-0.93 μM range) proved to be potentially powerful inhibitors also against CK1 (IC50 in the 18.4-2.2 μM range).
